Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

The Issue of Extrusion and Dislocation in Titanium Middle Ear Prostheses: A Literature Review

Pietro Canzi
,
Elena Carlotto
* ,
Luca Bruschini
ORCID logo ,
Domenico Minervini
,
Mario Mosconi
,
Laura Caliogna
,
Ilaria Ottoboni
,
Cesare Chiapperini
,
Francesco Lazzerini
,
Francesca Forli
,
Stefano Berrettini
,
Marco Benazzo
Version 1 : Received: 11 September 2023 / Approved: 13 September 2023 / Online: 14 September 2023 (03:47:04 CEST)

A peer-reviewed article of this Preprint also exists.

Canzi, P.; Carlotto, E.; Bruschini, L.; Minervini, D.; Mosconi, M.; Caliogna, L.; Ottoboni, I.; Chiapperini, C.; Lazzerini, F.; Forli, F.; Berrettini, S.; Benazzo, M. Extrusion and Dislocation in Titanium Middle Ear Prostheses: A Literature Review. Brain Sci. 2023, 13, 1476. Canzi, P.; Carlotto, E.; Bruschini, L.; Minervini, D.; Mosconi, M.; Caliogna, L.; Ottoboni, I.; Chiapperini, C.; Lazzerini, F.; Forli, F.; Berrettini, S.; Benazzo, M. Extrusion and Dislocation in Titanium Middle Ear Prostheses: A Literature Review. Brain Sci. 2023, 13, 1476.

Abstract

Titanium middle ear prostheses are widely used in surgical practice due to their acoustic properties. However, they present a significant drawback shared by all synthetic materials currently in use for middle ear reconstruction: they can be rejected by the organism of the host. In this study, we aim to review the current literature on titanium TORP and PORP extrusion and dislocation. Eighty-one articles were analysed after full article review based on the inclusion and exclusion criteria. The most common indication for reconstruction was chronic otitis media with cholesteatoma. The average extrusion or dislocation rate was 5.1%, ranging from 0 to 35%. The average improvement in air-bone gap was 12.3 dB (1.6 dB to 25.1 dB) and 13.7 (-0,5 dB to 22.7 dB) for PORP ad TORP groups, respectively. The data reported on this topic are highly variable, demonstrating the functional outcomes are difficult to predict in clinical practice. We believe the current limitations could be overcome with technological developments, including bioengineering research focused on promoting the prothesis adaptation to the ME environment.

Keywords

middle ear; ossicular replacement prosthesis; titanium; extrusion; dislocation; complication; hearing

Subject

Medicine and Pharmacology, Otolaryngology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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