Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Predictors of 30-Day Postoperative Outcome after Elective Endovascular Abdominal Aortic Aneurysm Repair; a Tertiary Referral Center Experience

Maria P Ntalouka
ORCID logo ,
Petroula Nana
ORCID logo ,
Alexandros Brotis
,
Athanasios Chatzis
,
Maria Mermiri
ORCID logo ,
Konstantinos Stamoulis
,
Metaxia Bareka
ORCID logo ,
Athanasios Giannoukas
,
Miltiadis Matsagkas
,
Eleni Arnaoutoglou
*
Version 1 : Received: 3 September 2023 / Approved: 5 September 2023 / Online: 6 September 2023 (08:52:24 CEST)

A peer-reviewed article of this Preprint also exists.

Ntalouka, M.P.; Nana, P.; Brotis, A.; Chatzis, A.; Mermiri, M.; Stamoulis, K.; Bareka, M.; Giannoukas, A.; Matsagkas, M.; Arnaoutoglou, E. Predictors of 30-Day Postoperative Outcome after Elective Endovascular Abdominal Aortic Aneurysm Repair: A Tertiary Referral Center Experience. J. Clin. Med. 2023, 12, 6004. Ntalouka, M.P.; Nana, P.; Brotis, A.; Chatzis, A.; Mermiri, M.; Stamoulis, K.; Bareka, M.; Giannoukas, A.; Matsagkas, M.; Arnaoutoglou, E. Predictors of 30-Day Postoperative Outcome after Elective Endovascular Abdominal Aortic Aneurysm Repair: A Tertiary Referral Center Experience. J. Clin. Med. 2023, 12, 6004.

Abstract

The 30-day postoperative outcome after elective endovascular aneurysm repair (EVAR) was evaluated and the possible predictors were identified. Demographics, medical history, laboratory values, length of hospitalization (LOH), intensive care unit (ICU) admission and 30-day complications, classified as major [major adverse cardiovascular events (MACE), acute kidney injury (AKI) and death of any cause] and minor [post-implantation syndrome (PIS), postoperative delirium (POD), urinary tract infection (UTI) and technical graft failure] were documented, respectively. We included 322 patients (median LOH 4 days). One-hundred and twenty one (37.5%) complications, mostly minor (n=103, 31.9%), were recorded. Eleven patients (3.4%) evolved MACE, 5 (1.6%) AKI and 2 patients (0.6%) died in ICU. Seventy-seven patients (23.9%) suffered from PIS, eleven from POD, 11 from UTI and 4 from technical graft failure. Multivariate logistic regression analysis revealed that aneurysm diameter (p=0.01) and past smoking (p=0.003) were predictors for postoperative complications. PAD was an independent predictor of MACE (p=0.003), preoperative neutrophil to lymphocyte ratio (NLR) value of AKI (p=0.003) and past smoking of PIS (p=0.008), respectively. Our study showed that 30-day morbidity after EVAR exceeded 35%. However, the majority of complications were classified as minor and the associated mortality was low. Aneurysm diameter and past smoking were independent predictors for postoperative outcome.

Keywords

abdominal aortic aneurysm; endovascular procedure; prognosis; complications, postoperative; acute kidney injury; biomarkers; myocardial infarction; arrhythmia; cerebrovascular accident

Subject

Medicine and Pharmacology, Anesthesiology and Pain Medicine

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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