Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Application Of Photodynamic Therapy In Pediatric Dentistry: Literature Review

Version 1 : Received: 7 August 2023 / Approved: 7 August 2023 / Online: 8 August 2023 (14:16:31 CEST)

A peer-reviewed article of this Preprint also exists.

Silva, T.; Lunardi, A.J.L.; Barros, A.C.S.M.; Mandetta, A.R.H.; Grudzien, E.; San-Martín, M.; Horliana, A.C.R.T.; Bussadori, S.K.; Motta, L.J. Application of Photodynamic Therapy in Pediatric Dentistry: Literature Review. Pharmaceutics 2023, 15, 2335. Silva, T.; Lunardi, A.J.L.; Barros, A.C.S.M.; Mandetta, A.R.H.; Grudzien, E.; San-Martín, M.; Horliana, A.C.R.T.; Bussadori, S.K.; Motta, L.J. Application of Photodynamic Therapy in Pediatric Dentistry: Literature Review. Pharmaceutics 2023, 15, 2335.

Abstract

Microbiological control of dental pathologies presents a significant clinical challenge for dental surgeons, particularly considering drug-resistant microorganisms. To address this issue, Antimi-crobial Photodynamic Therapy (PDT) has emerged as an effective and complementary technique for microbial reduction. This therapy involves the application of a photosensitizer dye (PS) either topically or systemically, followed by exposure to low-power lasers with appropriate visible light wavelengths. PDT has found a valuable place in dentistry across various specialties, including surgery, periodontics, endodontics, dentistry, implantology, orthodontics, and pediatrics. In the realm of pediatric dentistry, managing microorganisms during dental treatments has become a major challenge.This article reviews the evidence supporting the potential of photodynamic therapy in combating bacteria, fungi, and viruses, with a particular focus on areas such as endodontics, restoration in deciduous teeth, implantology, and periodontics for bacterial control. Additionally, PDT has shown promise in stomatology, specifically in the treatment of mucositis and herpes. Considering its promising results and ease of application, photodynamic therapy presents an in-teresting alternative for clinical practice. However, it is important to note that specific protocols must be followed for each application, encompassing the type of photosensitizer, concentration, pre-irradiation time, light type, wavelength, energy, power, and mode of light delivery. Researchers have been steadily refining these protocols to facilitate PDT's integration into clinical practice.

Keywords

Photodynamic Therapy; Pediatric Dentistry; oral health; dental care

Subject

Medicine and Pharmacology, Dentistry and Oral Surgery

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