Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

What Are the Causes of Death Among Patients Admitted to a Contemporary Tertiary Level Cardiology Department? An Analysis of 10 Years of Morbidity & Mortality Meetings

Version 1 : Received: 27 July 2023 / Approved: 28 July 2023 / Online: 31 July 2023 (09:46:01 CEST)

A peer-reviewed article of this Preprint also exists.

Kwok, C.S.; Tafuro, J.; Wong, C.W.; Bennett, S.; Zachariah, D.; Barker, D.; Morley-Davies, A.; Satchithananda, D.; Gunning, M.; Borovac, J.A. What Are the Causes of Death among Patients Admitted to a Contemporary Tertiary-Level Cardiology Department? An Analysis of 10 Years of Morbidity and Mortality Meetings. Pathophysiology 2023, 30, 467-479. Kwok, C.S.; Tafuro, J.; Wong, C.W.; Bennett, S.; Zachariah, D.; Barker, D.; Morley-Davies, A.; Satchithananda, D.; Gunning, M.; Borovac, J.A. What Are the Causes of Death among Patients Admitted to a Contemporary Tertiary-Level Cardiology Department? An Analysis of 10 Years of Morbidity and Mortality Meetings. Pathophysiology 2023, 30, 467-479.

Abstract

Despite the efforts to deliver the best evidence-based care, in-hospital death is an inevitable event among some patients hospitalized in cardiology departments. We retrospectively evaluated mortality events from inpatient admissions to Cardiology Department between 2010-2019. Data were collected from morbidity & mortality meeting presentations which evaluated comorbidities, medical history, treatments, and causes of death for the overall cohort and according to age group and sex. There were 1,182 registered deaths. The most common causes of death among patients were acute myocardial infarction (AMI) (53.0%), heart failure (HF, 11.7%), cardiac arrest (CA, 6.6%), HF with complication/defined cardiomyopathy (6.3%) and sepsis (4.4%). We observed a decline in deaths from AMI from 61.9% in 2010 to 46.7% in 2019 while there was an apparent increase in deaths from HF (11.1% in 2010 to 25.9% in 2019). Compared to patients ≥65 years, younger patients were more likely to have died from CA (15.7% vs. 4.3%, p<0.001) and other cardiac reasons (3.0% vs. 0.4%, p<0.001). The majority of deaths were due to AMI, HF, and CA. We observed a significant decline in the proportion of deaths due to AMI in recent years with an increase in deaths due to HF.

Keywords

death; acute myocardial infarction; heart failure; cardiac arrest; cardiovascular departments; sepsis; causes of death; outcomes; medical ward

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

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