Nappi, F.; Avtaar Singh, S.S.; Jitendra, V.; Alzamil, A.; Schoell, T. The Roles of microRNAs in the Cardiovascular System. Int. J. Mol. Sci.2023, 24, 14277.
Nappi, F.; Avtaar Singh, S.S.; Jitendra, V.; Alzamil, A.; Schoell, T. The Roles of microRNAs in the Cardiovascular System. Int. J. Mol. Sci. 2023, 24, 14277.
Nappi, F.; Avtaar Singh, S.S.; Jitendra, V.; Alzamil, A.; Schoell, T. The Roles of microRNAs in the Cardiovascular System. Int. J. Mol. Sci.2023, 24, 14277.
Nappi, F.; Avtaar Singh, S.S.; Jitendra, V.; Alzamil, A.; Schoell, T. The Roles of microRNAs in the Cardiovascular System. Int. J. Mol. Sci. 2023, 24, 14277.
Abstract
The discovery of microRNAs and their role in disease today represents a substantial breakthrough that has inspired and propagating research on microRNAs as targets for diagnosis and therapy. Cardiovascular disease is an area where the limitations of early diagnosis and conventional pharmacotherapy are evident and deserve attention. Thus microRNA-based drugs have substantial potential for development. Research and its application can progress considerably as witnessed in preclinical and clinical trials. The use of miRNAs remains experimental at the time of writing but has a promising role in the diagnosis and prognosis of a variety of acute coronary syndrome presentations. Its use, alone or in combination with currently available biomarkers, could be adopted soon, especially if diagnostic ambiguity exists. In this review, we explore the current state of knowledge about microRNAs as potential targets for diagnosis and therapy in the cardiovascular system. We report recent improvements in the acknowledgment and characterization of microRNAs focusing on clinical translation. The new dares and outlooks toward clinical application are discussed.
Medicine and Pharmacology, Cardiac and Cardiovascular Systems
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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