Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Cost-Utility of Monulpiravir in COVID-19 Treatment: An Estimation in Vietnam Situation

Nam Xuan Vo
* ORCID logo ,
Ngan Nguyen Hoang Le
,
Trinh Dang Phuong Chu
,
Huong Lai Pham
,
Khang Xuan An Dinh
,
Tu Kim Tran
,
Tien Thuy Bui
Version 1 : Received: 21 June 2023 / Approved: 21 June 2023 / Online: 21 June 2023 (15:34:48 CEST)

How to cite: Vo, N.X.; Le, N.N.H.; Chu, T.D.P.; Pham, H.L.; Dinh, K.X.A.; Tran, T.K.; Bui, T.T. Cost-Utility of Monulpiravir in COVID-19 Treatment: An Estimation in Vietnam Situation. Preprints 2023, 2023061574. https://doi.org/10.20944/preprints202306.1574.v1 Vo, N.X.; Le, N.N.H.; Chu, T.D.P.; Pham, H.L.; Dinh, K.X.A.; Tran, T.K.; Bui, T.T. Cost-Utility of Monulpiravir in COVID-19 Treatment: An Estimation in Vietnam Situation. Preprints 2023, 2023061574. https://doi.org/10.20944/preprints202306.1574.v1

Abstract

The COVID-19 pandemic has expanded globally and caused serious consequence in both health system and the economy. MPV is one of two oral antivirals for COVID-19 with mild-to-moderate symptoms that have received FDA approval so far. This study aims to evaluate the cost-utility of using MPV in COVID-19 treatment. To compare the utility costs of MPV and non-MPV treatments for COVID-19 patients, we used a decision tree model. Data on clinical efficacy, cost, and quality of life were gathered from previous studies. The incremental effective cost ratio (ICER) calculated based on costs incurred and quality-adjusted life years (QALY), was considered as primary out-come. The total cost of MPV treatment and not using MPV was 15,362,516 VND (618 USD) and 15,771,262 VND (634 USD), respectively. The estimated QALY with using-MPV was 28.33, while without MPV was 19.72. The ICER was dominant, resulting in savings of 47,453 VND/QALY (1.9 USD). MPV is a cost-effective medication used to treat COVID-19. In mild-to-moderate COVID-19 patients, MPV considerably lowers costs and improves quality of life. However, several clinical factors of the drug still need to be taken into account.

Keywords

Cost-utility; Covid-19; Molnupiravir; Vietnam; Utility

Subject

Medicine and Pharmacology, Pharmacy

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Download PDF

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0
Get PDF Cite Share 0
Bookmark BibSonomy Mendeley Reddit Delicious
×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.