Version 1
: Received: 15 June 2023 / Approved: 16 June 2023 / Online: 16 June 2023 (03:39:21 CEST)
How to cite:
Di Giulio, F.; Castellini, C.; Tienforti, D.; Antolini, F.; Felzani, G.; Baroni, M.G.; Barbonetti, A. Clinical Correlates of Metabolic Syndrome in Men with Spinal Cord Injury. Preprints2023, 2023061163. https://doi.org/10.20944/preprints202306.1163.v1
Di Giulio, F.; Castellini, C.; Tienforti, D.; Antolini, F.; Felzani, G.; Baroni, M.G.; Barbonetti, A. Clinical Correlates of Metabolic Syndrome in Men with Spinal Cord Injury. Preprints 2023, 2023061163. https://doi.org/10.20944/preprints202306.1163.v1
Di Giulio, F.; Castellini, C.; Tienforti, D.; Antolini, F.; Felzani, G.; Baroni, M.G.; Barbonetti, A. Clinical Correlates of Metabolic Syndrome in Men with Spinal Cord Injury. Preprints2023, 2023061163. https://doi.org/10.20944/preprints202306.1163.v1
APA Style
Di Giulio, F., Castellini, C., Tienforti, D., Antolini, F., Felzani, G., Baroni, M.G., & Barbonetti, A. (2023). Clinical Correlates of Metabolic Syndrome in Men with Spinal Cord Injury. Preprints. https://doi.org/10.20944/preprints202306.1163.v1
Chicago/Turabian Style
Di Giulio, F., Marco Giorgio Baroni and Arcangelo Barbonetti. 2023 "Clinical Correlates of Metabolic Syndrome in Men with Spinal Cord Injury" Preprints. https://doi.org/10.20944/preprints202306.1163.v1
Abstract
Background: The diagnosis of metabolic syndrome (MetS) is a challenge in people with spinal cord injury (SCI). We aimed at identifying clinical risk factors or early markers of MetS in SCI that would facilitate a timely diagnosis and implementation of preventive/therapeutic strategies.
Methods: 168 patients with chronic (>1 year) SCI underwent clinical and biochemical evaluations. MetS was diagnosed according to modified criteria of the International Diabetes Federation validated in people with SCI.
Results: MetS was diagnosed in 56 of 132 men (42.4%) and 17 of 36 women (47.2%). At univariate regression analyses, putative predictors of MetS were an older age, a higher number of comorbidities, a lower insulin-sensitivity, the presence and intensity of pain, a shorter injury duration, a poorer leisure time physical activity (LTPA) and an incomplete motor injury. At the multiple regression analysis, a significant independent association with MetS only persisted for a poorer LTPA in minutes/week (OR: 0.998, 95%CI: 0.996, 0.999) and more severe pain symptoms as assessed by numeral rating scale (OR: 1.353, 95%CI: 1.085, 1.793).
Conclusions: In patients with SCI, intense pain symptoms and poor LTPA may suggest a high likelihood of MetS, regardless of age, SCI duration, motor disability degree, insu-lin-sensitivity and comorbidities.
Medicine and Pharmacology, Endocrinology and Metabolism
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
,
*
