Wireless Device with Energy Management for Closed-Loop Deep Brain Stimulation (CLDBS)

Tiago Matheus Nordi; Gabriel Augusto Ginja; Rodrigo Gounella; Erich Talanoni Fonoff; Eduardo Colombari; Melkzedekue M. Alcântara Moreira; Jose A. Afonso; Vitor Monteiro; Joao L. Afonso; João Paulo Carmo

doi:10.20944/preprints202306.0830.v1

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preprints.org > engineering > electrical and electronic engineering > doi: 10.20944/preprints202306.0830.v1

Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Wireless Device with Energy Management for Closed-Loop Deep Brain Stimulation (CLDBS)

Tiago Matheus Nordi

Gabriel Augusto Ginja

Rodrigo Gounella

Erich Talanoni Fonoff

Eduardo Colombari

Melkzedekue M. Alcântara Moreira

^* ,

^* ,

Version 1 : Received: 9 June 2023 / Approved: 12 June 2023 / Online: 12 June 2023 (11:11:09 CEST)

A peer-reviewed article of this Preprint also exists.

Matheus Nordi, T.; Augusto Ginja, G.; Gounella, R.; Talanoni Fonoff, E.; Colombari, E.; Moreira, M.M.A.; Afonso, J.A.; Monteiro, V.; Afonso, J.L.; Carmo, J.P. Wireless Device with Energy Management for Closed-Loop Deep Brain Stimulation (CLDBS). Electronics 2023, 12, 3082. Matheus Nordi, T.; Augusto Ginja, G.; Gounella, R.; Talanoni Fonoff, E.; Colombari, E.; Moreira, M.M.A.; Afonso, J.A.; Monteiro, V.; Afonso, J.L.; Carmo, J.P. Wireless Device with Energy Management for Closed-Loop Deep Brain Stimulation (CLDBS). Electronics 2023, 12, 3082.

Abstract

Deep brain stimulation (DBS) is an effective and safe medical treatment that improves the lives of patients with a wide range of neurological and psychiatric diseases, and has been consolidated as a first-line tool in the last two decades. Closed loop deep brain stimulation (CLDBS) pushes this tool further by automatically adjusting the stimulation parameters to the brain response in real-time. This paper presents a CLDBS with 2 stimulation channels and 2 acquisition channels. Each channel has a low-noise amplifier (LNA) buffer in differential configuration to eliminate the DC signal component of the input. Energy management is efficiently done by the control and communication unit. The battery supports almost 9 hours with both the acquisition and stimulation circuits active. If only the stimulation circuit is used as an Open Loop DBS (OLDBS), the battery can hold sufficient voltage for 24 hours of operation. The whole system is low-cost and portable and therefore it could be used as a wearable.

Keywords

closed-loop deep brain stimulation (CLDBS); neurostimulatio; implantable devices; internet of things (IoT); energy management

Subject

Engineering, Electrical and Electronic Engineering

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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