Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Method of Implementing Nutrivigilance in the Romanian Food Industry and Healthcare Systems

Version 1 : Received: 12 June 2023 / Approved: 12 June 2023 / Online: 12 June 2023 (07:39:38 CEST)

How to cite: Matran, I.M.; Tarcea, M.; Buicu, F.C.; Parvu, S.; Ungureanu, S.G.; Cirnatu, D. Method of Implementing Nutrivigilance in the Romanian Food Industry and Healthcare Systems. Preprints 2023, 2023060792. https://doi.org/10.20944/preprints202306.0792.v1 Matran, I.M.; Tarcea, M.; Buicu, F.C.; Parvu, S.; Ungureanu, S.G.; Cirnatu, D. Method of Implementing Nutrivigilance in the Romanian Food Industry and Healthcare Systems. Preprints 2023, 2023060792. https://doi.org/10.20944/preprints202306.0792.v1

Abstract

Introduction: The assumption that food resources and dietary supplements are natural and do not have side effects, or do not interact with drugs, is wrong, and can lead to unplanned symptoms or even hospital admissions. Also, not communicating with the family doctor, or the pharmacist, can make their work considerably more difficult in establishing the correct treatment. Methods: PubMed, ResearchGate, EUR-Lex, and Memorial Sloan Kettering Cancer Center databases for scientific literature were analyzed, for the keywords "adverse reactions", nutrivigilance", and "drug interaction". The method proposed by us for the implementation of nutrivigilance in the re-search-development stage is the application and adaptation of HACCP principles (Hazard Analysis and Critical Control Points) to nutrivigilance. Results: The implementation of nutrivigilance in the Romanian food supplements industry and healthcare system represent a real tool for improving public health management by preventing adverse reactions, and reducing the costs of the health system. From our knowledge, the proposal regarding the implementation of nutrivigilance in the research stage of food and food supplements, based on the principles of HACCP is unique. Conclusions: We believe that the proposed method is useful starting with the research-development of food supplements, followed by post-sale analysis.

Keywords

nutrivigilance; adverse reactions; food supplements; HACCP

Subject

Medicine and Pharmacology, Dietetics and Nutrition

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