Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Cosmetics Pattern Map Considering their Effects on Skin Microbiota-Principal Component Analysis of the Effects on Short Chain Fatty Acid Production by Skin Microbiota Staphylococcus epidermidis

Version 1 : Received: 7 June 2023 / Approved: 8 June 2023 / Online: 8 June 2023 (04:09:58 CEST)

A peer-reviewed article of this Preprint also exists.

Tanabe, K.; Moriguchi, C.; Fujiyama, N.; Shigematsu, Y.; Haraguchi, N.; Hirano, Y.; Dai, H.; Inaba, S.; Tokudome, Y.; Kitagaki, H. A Trial for the Construction of a Cosmetic Pattern Map Considering Their Effects on Skin Microbiota—Principal Component Analysis of the Effects on Short-Chain Fatty Acid Production by Skin Microbiota Staphylococcus epidermidis. Fermentation 2023, 9, 647. Tanabe, K.; Moriguchi, C.; Fujiyama, N.; Shigematsu, Y.; Haraguchi, N.; Hirano, Y.; Dai, H.; Inaba, S.; Tokudome, Y.; Kitagaki, H. A Trial for the Construction of a Cosmetic Pattern Map Considering Their Effects on Skin Microbiota—Principal Component Analysis of the Effects on Short-Chain Fatty Acid Production by Skin Microbiota Staphylococcus epidermidis. Fermentation 2023, 9, 647.

Abstract

Cosmetics have various characters, but there have been no studies which classified the properties of cosmetics based on their effects on skin-domesticated bacteria. In this study, we established an anaerobic culture and short-chain fatty acid measurement system using Staphylococcus epidermidis, a representative bacterium of indigenous skin bacteria. Furthermore, this system was used to extract and classify the characteristics of 9 cosmetics. Cosmetics containing ferments of rice and soy were clustered in the vicinity, although one cosmetic containing soy ferment was clustered distant from other similar cosmetics. Cosmetics from South Asia and those containing natural plant extracts were clustered in the vicinity. These results show that this method can be utilized as a cosmetics pattern map, and will provide a method to prevent growth of opportunistic bacteria.

Keywords

cosmetics; skin microbiota; Staphylococcus epidermidis; lactic acid; PCA

Subject

Medicine and Pharmacology, Dermatology

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