Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

In-Hospital Rehabilitation of Patients with COVID-19: A Retrospective Study with Propensity Score Matching

Sergey M. Konev
,
Elisaveta S. Koneva
,
Teimurazi R. Matsonashvili
,
Ekaterina N. Zhumanova
,
Danil S. Malyutin
* ,
Natalia S. Serova
,
Evgeny E. Achkasov
,
Igor V. Semenyakin
,
Konstantin V. Lyadov
,
Irina A. Mandel
,
Andrey I Yaroshetskiy
Version 1 : Received: 2 June 2023 / Approved: 5 June 2023 / Online: 5 June 2023 (08:06:38 CEST)

How to cite: Konev, S. M.; Koneva, E. S.; Matsonashvili, T. R.; Zhumanova, E. N.; Malyutin, D. S.; Serova, N. S.; Achkasov, E. E.; Semenyakin, I. V.; Lyadov, K. V.; Mandel, I. A.; Yaroshetskiy, A. I. In-Hospital Rehabilitation of Patients with COVID-19: A Retrospective Study with Propensity Score Matching. Preprints 2023, 2023060261. https://doi.org/10.20944/preprints202306.0261.v1 Konev, S. M.; Koneva, E. S.; Matsonashvili, T. R.; Zhumanova, E. N.; Malyutin, D. S.; Serova, N. S.; Achkasov, E. E.; Semenyakin, I. V.; Lyadov, K. V.; Mandel, I. A.; Yaroshetskiy, A. I. In-Hospital Rehabilitation of Patients with COVID-19: A Retrospective Study with Propensity Score Matching. Preprints 2023, 2023060261. https://doi.org/10.20944/preprints202306.0261.v1

Abstract

Background: Early rehabilitation is an important strategy for the treatment of severe diseases. The study aimed to assess the efficacy of early rehabilitation of patients with mild-to-moderate COVID-19. Methods: The retrospective single-center study with propensity score matching. Results: 180 patients (54 (44 - 62.3) yo) divided into three equal groups: 1 - physical exercises; 2 - physical exercises and chest massage in an electrostatic field; 3 - no rehabilitation. The length of stay (LOS) in the hospital in group 1 was 14 (11-15) days, group 2 - 13 (11-15) days, group 3 - 15 (13-18) days, p=0.0026. Physical exercises for patients with CT-1 improved the quality of life, assessed by the EQ-5D questionnaire, by reducing the level of anxiety and depression. The Hazard Ratio (HR) for desaturation (<93%) was 2.34 (95% Confidence Interval (CI) 1.18-4.63) for group 2, p=0.001. The HR for C-reactive protein level above 50 mg/l in patients with CT-2 was 2.33 (95% CI 1.56-3.47), p=0.0001. Conclusions: Rehabilitation programs are safe for СOVID-19-patients; reduce hospital LOS; improve the quality of life. Continuous monitoring of a patient's condition during rehabilitation is essential. ClinicalTrials.gov ID: NCT0580836

Keywords

COVID-19; early rehabilitation; computed tomography; physical exercises; chest massage in an electrostatic field.

Subject

Medicine and Pharmacology, Clinical Medicine

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Download PDF

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Get PDF Cite Share 0
Bookmark BibSonomy Mendeley Reddit Delicious
×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.