Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Overview of Caffeine Effects on Human Health and Emerging Delivery Strategies

Version 1 : Received: 17 May 2023 / Approved: 17 May 2023 / Online: 17 May 2023 (14:19:41 CEST)

How to cite: Saraiva, S.M.; Jacinto, T.A.; Gonçalves, A.C.; Gaspar, D.; Silva, L.R. Overview of Caffeine Effects on Human Health and Emerging Delivery Strategies. Preprints 2023, 2023051255. https://doi.org/10.20944/preprints202305.1255.v1 Saraiva, S.M.; Jacinto, T.A.; Gonçalves, A.C.; Gaspar, D.; Silva, L.R. Overview of Caffeine Effects on Human Health and Emerging Delivery Strategies. Preprints 2023, 2023051255. https://doi.org/10.20944/preprints202305.1255.v1

Abstract

Caffeine is a naturally occurring alkaloid found in various plants. It acts as a stimulant, antioxidant, anti-inflammatory and even an aid in pain management, and is found in several over-the-counter medications. This naturally derived bioactive compound is the best-known ingredient in coffee and other beverages, such as tea, soft drinks, and energy drinks, and is the most widely consumed substance worldwide. Therefore, it is extremely important to research the effects of this substance on the human body. With this in mind, caffeine and its derivatives have been extensively studied to evaluate its ability to prevent diseases and exert anti-aging and neuroprotective effects. This review is intended to provide an overview of the effects of caffeine on cancer, cardiovascular, immunological, inflammatory, and neurological diseases, among others. The heavily researched area of caffeine in sports will also be discussed. Finally, recent advances in the development of novel formulations, in the form of dietary supplements of caffeine and nanocarriers, to enhance the bioavailability of caffeine and its beneficial effects will be discussed. On the other hand, caffeine may contribute to elevated blood pressure, anemia, and migraine.

Keywords

caffeine; health benefits; athletics effects; dietary supplements; nanocarriers

Subject

Medicine and Pharmacology, Medicine and Pharmacology

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.