Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

N-Doped Carbon Nanoparticles As Antibacterial Agents: The Role of the Chemical Composition on the Antibacterial Activity

Version 1 : Received: 15 May 2023 / Approved: 16 May 2023 / Online: 16 May 2023 (04:53:48 CEST)

A peer-reviewed article of this Preprint also exists.

Lopez-Diaz, D.; Merchán, M.D.; Pérez, P.; Velázquez, M.M. N-Doped Carbon Nanoparticles as Antibacterial Agents on Escherichia coli: The Role of the Size and Chemical Composition of Nanoparticles. Coatings 2023, 13, 1169. Lopez-Diaz, D.; Merchán, M.D.; Pérez, P.; Velázquez, M.M. N-Doped Carbon Nanoparticles as Antibacterial Agents on Escherichia coli: The Role of the Size and Chemical Composition of Nanoparticles. Coatings 2023, 13, 1169.

Abstract

Graphene-based nanomaterials have emerged as promising materials for a wide range of applications.. Therefore, in the last years carbon nanoparticles have attracted great attention due to their low toxicity, high biocompatibility and easy preparation. Recently, N-doped carbon nanoparticles have been shown to have improved antibacterial activity over the undoped nanomaterial, but it is difficult to find correlations between the structure of the nanoparticle and its antibacterial activity. With this purpose, here, we analyze the effect of both, the nanoparticle size and the surface chemical composition of four N-doped carbon nanoparticles on the growth of Escherichia coli bacteria. Our results were analyzed using a Ligand-Substrate model based on the Monod´s equation, which allows us to interpret the dependence of the nanoparticle-bacteria affinity with the nanomaterial structure.

Keywords

N-doped graphene carbon nanoparticles; antibacterial ability; Escherichia coli

Subject

Chemistry and Materials Science, Physical Chemistry

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