PreprintArticleVersion 1Preserved in Portico This version is not peer-reviewed
The Impact of the Association Between Structural Changes in Glaucoma as a Primary Element in Visual Perception and Audi-Tory Function on the Diagnostic Management of Glaucomatous Disease
Version 1
: Received: 11 May 2023 / Approved: 12 May 2023 / Online: 12 May 2023 (05:18:02 CEST)
How to cite:
Neacsu¹´², A.M.; Anton³, N.; Lapusneanu², L.; Stoian², V.; Andrei², M.C.; Cosman², M.; Ferechide², D. The Impact of the Association Between Structural Changes in Glaucoma as a Primary Element in Visual Perception and Audi-Tory Function on the Diagnostic Management of Glaucomatous Disease. Preprints2023, 2023050891. https://doi.org/10.20944/preprints202305.0891.v1
Neacsu¹´², A.M.; Anton³, N.; Lapusneanu², L.; Stoian², V.; Andrei², M.C.; Cosman², M.; Ferechide², D. The Impact of the Association Between Structural Changes in Glaucoma as a Primary Element in Visual Perception and Audi-Tory Function on the Diagnostic Management of Glaucomatous Disease. Preprints 2023, 2023050891. https://doi.org/10.20944/preprints202305.0891.v1
Neacsu¹´², A.M.; Anton³, N.; Lapusneanu², L.; Stoian², V.; Andrei², M.C.; Cosman², M.; Ferechide², D. The Impact of the Association Between Structural Changes in Glaucoma as a Primary Element in Visual Perception and Audi-Tory Function on the Diagnostic Management of Glaucomatous Disease. Preprints2023, 2023050891. https://doi.org/10.20944/preprints202305.0891.v1
APA Style
Neacsu¹´², A.M., Anton³, N., Lapusneanu², L., Stoian², V., Andrei², M.C., Cosman², M., & Ferechide², D. (2023). The Impact of the Association Between Structural Changes in Glaucoma as a Primary Element in Visual Perception and Audi-Tory Function on the Diagnostic Management of Glaucomatous Disease. Preprints. https://doi.org/10.20944/preprints202305.0891.v1
Chicago/Turabian Style
Neacsu¹´², A.M., Mihaela Cosman² and Dumitru Ferechide². 2023 "The Impact of the Association Between Structural Changes in Glaucoma as a Primary Element in Visual Perception and Audi-Tory Function on the Diagnostic Management of Glaucomatous Disease" Preprints. https://doi.org/10.20944/preprints202305.0891.v1
Abstract
Background. In the last decade, it was concluded that glaucomatous optic neuropathy is part of the neurodegenerative diseases in which destructive neuronal lesions are located not only in the structure of the retina, but they are also present at the level of the central visual and nervous pathways. Patients with Primitive Open Angle Glaucoma may have experienced changes such as sensorineural hearing loss as well as balance changes. The purpose of this study is to evaluate the degree of involvement of the auditory system in patients with glaucoma, the structural changes in the optic nerve and, to establish correlation between the hearing loss and structural changes in the optic nerve. The subjects included in the study are grouped as follows: a group of patients with glaucoma that will be compared to a group of patients without glaucoma only as well as identi-fy-ing the evolution of structural changes in optic nerve to patients with glaucoma and to normal patients. Material and methods. It is a prospective, cross-sectional study on 32 eyes of 16 subjects with Primitive Open Angle Glaucoma in a study group and 24 eyes of 12 healthy subjects in con-trol group with a mean age of 62 years in both groups. Both groups underwent ophthalmo-logical, audiological and radio imaging evaluation: Pure-tone audiometry (PTA) were recorded, oph-thalmologic evaluations according to a standardized protocol and MRI cerebral examination was performed. Results: In the Study group patients, compared to the Control group, the average lev-els of the left PTA, the cup/disc (C/D) area in both eyes, the C/D ratio in both eyes are in-creased. The mean level of Retinal nerve fiber layer (RNFL) mean thickness was slightly lower in patients with glaucoma. Multivariate analysis demonstrates that gender can be a good predictor of C/D area, gender and age can be good predictors of PTA both eyes and C/D ratio in the right eye, and gender, age and background can be good predictors of disc area in the left eye. Conclu-sions: Pa-tients with Primitive Open Angle Glaucoma show changes in audiometry test in correla-tion with ophthalmological parameters demonstrating that the auditory system can be affected in Primitive Open Angle Glaucoma. This study emphasizes the problem of interdisciplinarity in medicine with the aim of ensuring the quality of life of patients with glaucoma. A good collabora-tion between ophthalmologist and otolaryngologist will be very useful for these patients.
Keywords
hearing loss; pure tone audiometry; structural changes in the optic nerve; RNFL; C/D ratio
Subject
Medicine and Pharmacology, Neuroscience and Neurology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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