Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

High Frequency of Osteophytes Detected by High Resolution Ul-Trasound at the Finger Joints of Asymptomatic Factory Workers

Version 1 : Received: 8 May 2023 / Approved: 9 May 2023 / Online: 9 May 2023 (08:44:35 CEST)

How to cite: Giulini, M.; Brinks, R.; Vordenbäumen, S.; Acar, H.; Richter, J.G.; Feldhaus, C.; Baraliakos, X.; Ostendorf, B.; Schneider, M.; Sander, O.; Sewerin, P. High Frequency of Osteophytes Detected by High Resolution Ul-Trasound at the Finger Joints of Asymptomatic Factory Workers. Preprints 2023, 2023050612. https://doi.org/10.20944/preprints202305.0612.v1 Giulini, M.; Brinks, R.; Vordenbäumen, S.; Acar, H.; Richter, J.G.; Feldhaus, C.; Baraliakos, X.; Ostendorf, B.; Schneider, M.; Sander, O.; Sewerin, P. High Frequency of Osteophytes Detected by High Resolution Ul-Trasound at the Finger Joints of Asymptomatic Factory Workers. Preprints 2023, 2023050612. https://doi.org/10.20944/preprints202305.0612.v1

Abstract

Osteoarthritis of the hand (HOA) is one of the most common musculoskeletal diseases affecting health. Osteophytes, documented by imaging procedures are often used as diagnostic criteria. The gold standard is the radiographic image, however, more sensitive and saver methods such as ultrasound are gaining in importance. We investigated the prevalence, grade and pattern of osteophytes by high resolution ultrasound investigation (US) in a population-based cross-sectional study. Factory workers were recruited at work. 26 finger joints of each participant were examined with US with grading the occurrence of osteophytes in a semiquantitative score ranging 0-3, increasing scores indicated larger osteophytes. 427 participants (mean age 53.5 years, range. 20-79 years) were investigated, resulting in 11,000 scored joints. At least one osteophyte was found in 4,546/11,000 (41.3%) joints or 426/427 (99.8%) participants but grade 2 or 3 osteophytes were seen in only 553 (5.0%) joints. The number of os-teophyte sum score increased with age (0.18/year of age increase, p<0.001). Distal interphalange-al joints (DIP) were predominantly affected with 61%, followed by proximal interphalangeal joints (PIP) with 48%, carpometacarpal joint 1 (CMC1) with 39% and metacarpophalangeal joints (MCP) with 16%. In conclusion, US is a feasible screening tool for osteophytes and HOA. Grade 1 osteophytes are a common finding in the working population when assessed by ultrasound and their prevalence is increasing with age. Prevalence of grade 2 or 3 osteophytes is less common and reflects clini-cal presence of HOA. Follow up investigations are necessary to recognize the predictive rele-vance of early osteophytes.

Keywords

Osteoarthritis; screening; prevalence; ultrasound; imaging; osteophytes

Subject

Medicine and Pharmacology, Epidemiology and Infectious Diseases

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