Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Understanding Feline Infectious Peritonitis: Serotypes, Patho-genicity, and Diagnostic Challenges

Version 1 : Received: 5 May 2023 / Approved: 8 May 2023 / Online: 8 May 2023 (10:32:09 CEST)

How to cite: Li, S.; Cui, Y.; Zhou, J.; Hou, L.; Feng, X.; Liu, J. Understanding Feline Infectious Peritonitis: Serotypes, Patho-genicity, and Diagnostic Challenges. Preprints 2023, 2023050519. https://doi.org/10.20944/preprints202305.0519.v1 Li, S.; Cui, Y.; Zhou, J.; Hou, L.; Feng, X.; Liu, J. Understanding Feline Infectious Peritonitis: Serotypes, Patho-genicity, and Diagnostic Challenges. Preprints 2023, 2023050519. https://doi.org/10.20944/preprints202305.0519.v1

Abstract

Feline infectious peritonitis (FIP), caused by the feline coronavirus (FCoV), is a devastating dis-ease in cats. Based on its antigenicity, FCoV can be divided into two serotypes: FCoV-I and FCoV-II. Furthermore, according to its pathogenicity, FCoV can be divided into feline enteric coronavirus (FECV) and feline infectious peritonitis virus (FIPV). There are numerous factors that affect the pathogenesis of FIP, among which host immunity and viral genetics can play an es-sential role in the development of FIP. Owing to the lack of specific symptoms, existing individual diagnostic methods can only support the suspicion of FIP, and multiple diagnostic methods and test data need to be combined to make a diagnosis. Although there are still no effective FIPV vaccines or commercial drugs available in the market, various studies have shown that some compounds can be used for treatment. Therefore, FIP is no longer incurable in cats

Keywords

FIP; FCoV; genotype; pathogenesis; diagnosis; treatment; vaccine

Subject

Biology and Life Sciences, Animal Science, Veterinary Science and Zoology

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