Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

To Explore the Efficacy of Modified Altemeier Procedure in the Treatment of Complete Rectal Prolapse

Version 1 : Received: 19 April 2023 / Approved: 19 April 2023 / Online: 19 April 2023 (08:48:14 CEST)

How to cite: Zhai, Y.; Wang, B.; Han, W.H.; Yu, B.; Liu, C.; Gao, Q.; Wang, S.; Fang, Y. To Explore the Efficacy of Modified Altemeier Procedure in the Treatment of Complete Rectal Prolapse. Preprints 2023, 2023040576. https://doi.org/10.20944/preprints202304.0576.v1 Zhai, Y.; Wang, B.; Han, W.H.; Yu, B.; Liu, C.; Gao, Q.; Wang, S.; Fang, Y. To Explore the Efficacy of Modified Altemeier Procedure in the Treatment of Complete Rectal Prolapse. Preprints 2023, 2023040576. https://doi.org/10.20944/preprints202304.0576.v1

Abstract

Abstract Objective:To explore the efficacy of modified Altemeier procedure in the treatment of complete rectal prolapse. Method and Main outcome measures:The enrolled patients with complete rectal prolapse were divided into traditional and modified groups according to the surgical approach.The primary outcomes included complication rates, time and severity of postoperative recurrence, changes in pre- and postoperative Wexner anal incontinence scores and ED-5Q-5L quality-of-life autonomy scores. Secondary outcomes included operative time, intraoperative bleeding, and length of hospital stay. Results:The overall complication rates were 33.33% and 6.67% and recurrence rates were 26.67% and 7% in the traditional and modified groups, respectively (P<0.05);The duration of surgery in the traditional group was shorter than that in the modified group, but the intraoperative bleeding was significantly higher than that in the modified group, and all differences were statistically significant (P<0.05);The length of stay and in the two groups, respectively, with no statistically significant difference (P>0.05);The postoperative Wexner incontinence score and ED-5Q-5L quality of life in the modified group were found to be significantly better than those in the traditional group at 8 months postoperative follow-up, with statistically significant differences (P<0.05). Conclusions:Pathological dilatation of the distal rectum may be another anatomical defect in complete rectal prolapse. The results of the clinical study confirmed the clinical effectiveness and safety of the modified Altmeyer procedure, which has high clinical application value.

Keywords

modified Altemeier procedure; complete rectal prolapse; surgical recurrence rates complication

Subject

Medicine and Pharmacology, Gastroenterology and Hepatology

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