Gałązka, A.; Jankiewicz, U.; Szczepkowski, A. Biochemical Characteristics of Laccases and Their Practical Application in the Removal of Xenobiotics from Water. Appl. Sci.2023, 13, 4394.
Gałązka, A.; Jankiewicz, U.; Szczepkowski, A. Biochemical Characteristics of Laccases and Their Practical Application in the Removal of Xenobiotics from Water. Appl. Sci. 2023, 13, 4394.
Gałązka, A.; Jankiewicz, U.; Szczepkowski, A. Biochemical Characteristics of Laccases and Their Practical Application in the Removal of Xenobiotics from Water. Appl. Sci.2023, 13, 4394.
Gałązka, A.; Jankiewicz, U.; Szczepkowski, A. Biochemical Characteristics of Laccases and Their Practical Application in the Removal of Xenobiotics from Water. Appl. Sci. 2023, 13, 4394.
Abstract
Industrialization, intensive farming, rapid population growth and urbanization are the source of a large number of pollutants entering the environment. The current concentration of xenobiotics released into the environment exceeds its natural ability to decompose them. Enzymatic degradation of pollutants seems to be an environmentally friendly process. Due to the wide spectrum of substrate specificity, from inorganic compounds to high molecular weight organic compounds such as PAH or dyes, as well as favorable biochemical properties, laccase has been used in the biological removal of xenobiotics from the environment. It is important to understand the degradation mechanisms of pollutants and to evaluate the final products in terms of their toxicity. The laccase oxidizes the substrates with the simultaneous reduction of molecular oxygen to water, which is the purest reaction co-substrate. That is why it is called a green biocatalyst. The trend is an increase in the production of enzymes related to the intensive development of industry, bioremediation or synthetic chemistry. This leads to the search for laccases with greater activity and stability under extreme conditions. The potential of laccases to degrade xenobiotics can be promoted by improving enzymatic catalytic characterization using protein engineering and other genetic engineering methods.
Keywords
laccase; xenobiotics; protein engineering
Subject
Biology and Life Sciences, Ecology, Evolution, Behavior and Systematics
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
