Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Review: Influence of Vitamin D Blood Concentration and Supplementation during Pregnancy on Preeclampsia Development and Neonatal Outcomes

Version 1 : Received: 4 October 2022 / Approved: 6 October 2022 / Online: 6 October 2022 (12:16:11 CEST)

A peer-reviewed article of this Preprint also exists.

Karpova, N.; Dmitrenko, O.; Arshinova, E.; Nurbekov, M. Review: Influence of 25(OH)D Blood Concentration and Supplementation during Pregnancy on Preeclampsia Development and Neonatal Outcomes. Int. J. Mol. Sci. 2022, 23, 12935. Karpova, N.; Dmitrenko, O.; Arshinova, E.; Nurbekov, M. Review: Influence of 25(OH)D Blood Concentration and Supplementation during Pregnancy on Preeclampsia Development and Neonatal Outcomes. Int. J. Mol. Sci. 2022, 23, 12935.

Abstract

Vitamin D plays an essential role in embryogenesis and the course of intra- and postnatal periods and is crucially involved in the functioning of the mother-placenta-fetus system. Low quantity of Vitamin D during pregnancy can lead to the elevated risk for preeclampsia occurence. Despite the numerous studies on the association of Vitamin D deficiency and preeclampsia development, the current research on this theme is contradictory. In this review we summarize and analyze study data on the effects of vitamin D deficiency and supplementation on pregnancy, labor, fetal and neonatal outcomes.

Keywords

preeclampsia; neonatal outcome; vitamin D; 25(OH)D, 1,25(OH)2D; diabetes; pregnancy complication; vitamin D deficiency; vitamin D supplementation

Subject

Biology and Life Sciences, Endocrinology and Metabolism

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