Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Action Potential and Water Molecules

Version 1 : Received: 28 August 2022 / Approved: 30 August 2022 / Online: 30 August 2022 (06:00:56 CEST)

How to cite: Tamagawa, H.; Nakahata, T.; Sugimori, R.; Delalande, B.; Mulembo, T. Action Potential and Water Molecules. Preprints 2022, 2022080510. https://doi.org/10.20944/preprints202208.0510.v1 Tamagawa, H.; Nakahata, T.; Sugimori, R.; Delalande, B.; Mulembo, T. Action Potential and Water Molecules. Preprints 2022, 2022080510. https://doi.org/10.20944/preprints202208.0510.v1

Abstract

The occurrence of potential spikes in a cell is a sign of life, and it is called action potential. There is a common notion that neuron signal conduction is the conduction of action potential. Hence, action potential is a typical and essential life activity. However, such potential spikes occur even in simple nonliving systems. According to the experimental observations by Pollack, structured water molecules can generate a negative potential environment. From this observation, the potential spike generation process for both living and nonliving systems caused by ion and water molecule adsorption-desorption process could be explained in this paper. So, taking into consideration the electrically neutral water molecules,the action potential generation mechanism could be explained. It is a fully inanimate model. Hence, the action potential may not be a life activity. Here, the role of water molecules in life is investigated further. It was found that the phase transition of the membrane is involved in the neuron signal conduction, but the membrane phase transition could be due to the change of state of the water molecules, which forms a large-scale structure in the cavities created by a number of lipids.

Keywords

membrane potential; water; adsorption; structured water

Subject

Biology and Life Sciences, Anatomy and Physiology

Comments (2)

Comment 1
Received: 31 August 2022
Commenter:
The commenter has declared there is no conflict of interests.
Comment: As a friendly criticism.

Critical problems of the membrane physiology of a living cell. https://youtu.be/OCqbYdItfvI
Neovitalism of the 21st Century. What does it mean? https://youtu.be/mEGU-AnbRuA
The great basic question of cell biology. https://youtu.be/DBoUTwT1YVA

Matveev, V.V. (2022). Membraneless physiology of the living cell. The past and the present. 4open, 5, 15. https://doi.org/10.1051/fopen/2022013
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Response 1 to Comment 1
Received: 1 September 2022
The commenter has declared there is no conflict of interests.
Comment: Thanks for your input.

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