Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Pressure Injury Link to Entropy of Abdominal Temperature

Version 1 : Received: 20 June 2022 / Approved: 22 June 2022 / Online: 22 June 2022 (09:52:15 CEST)

A peer-reviewed article of this Preprint also exists.

Padhye, N.; Rios, D.; Fay, V.; Hanneman, S.K. Pressure Injury Link to Entropy of Abdominal Temperature. Entropy 2022, 24, 1127. Padhye, N.; Rios, D.; Fay, V.; Hanneman, S.K. Pressure Injury Link to Entropy of Abdominal Temperature. Entropy 2022, 24, 1127.

Abstract

This study examined the association between pressure injuries and complexity of abdominal temperature measured in residents of a nursing facility. The temperature served as a proxy measure for skin thermoregulation. Refined multiscale sample entropy and bubble entropy were used to measure the complexity of the temperature time series measured over two days at 1-minute intervals. Robust summary measures were derived for the multiscale entropies and used in predictive models for pressure injuries that were built with adaptive lasso regression and neural networks. Both types of entropies were lower in the group of participants with pressure injuries (n=11) relative to the group of non-injured participants (n=15). This was generally true at the longer temporal scales, with the effect peaking at scale τ=23 minutes. Predictive models for pressure injury on the basis of refined multiscale sample entropy and bubble entropy yielded 92% accuracy, outperforming predictions based on any single measure of entropy. Combining entropy measures with a widely used risk assessment score led to the best prediction accuracy. Complexity of abdominal temperature series could therefore serve as an indicator of risk of pressure injury.

Keywords

refined multiscale entropy; sample entropy; bubble entropy; adaptive complex system; pressure ulcer; machine learning; body temperature

Subject

Public Health and Healthcare, Nursing

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