Version 1
: Received: 8 June 2022 / Approved: 16 June 2022 / Online: 16 June 2022 (10:54:10 CEST)
How to cite:
Passarelli, P.C.; D'Addona, A.; Svaluto Ferro, L.; Lopez, M.A. Management of Patients with Coagulation Disorders Undergoing Minor Oral Surgery. Preprints2022, 2022060239. https://doi.org/10.20944/preprints202206.0239.v1
Passarelli, P.C.; D'Addona, A.; Svaluto Ferro, L.; Lopez, M.A. Management of Patients with Coagulation Disorders Undergoing Minor Oral Surgery. Preprints 2022, 2022060239. https://doi.org/10.20944/preprints202206.0239.v1
Passarelli, P.C.; D'Addona, A.; Svaluto Ferro, L.; Lopez, M.A. Management of Patients with Coagulation Disorders Undergoing Minor Oral Surgery. Preprints2022, 2022060239. https://doi.org/10.20944/preprints202206.0239.v1
APA Style
Passarelli, P.C., D'Addona, A., Svaluto Ferro, L., & Lopez, M.A. (2022). Management of Patients with Coagulation Disorders Undergoing Minor Oral Surgery. Preprints. https://doi.org/10.20944/preprints202206.0239.v1
Chicago/Turabian Style
Passarelli, P.C., Luigi Svaluto Ferro and Michele Antonio Lopez. 2022 "Management of Patients with Coagulation Disorders Undergoing Minor Oral Surgery" Preprints. https://doi.org/10.20944/preprints202206.0239.v1
Abstract
Objective: The purpose of the present study was to analyze the management of dental extractions in patients affected by coagulation disorders in order to prevent bleeding intraoperative and postoperative complications. Subjects and Methods: This study included 17 patients with a diagnosis of a coagulation disorder, who had been subjected to a single or multiple dental extraction. Recombinant activated Factor VII was administered in those patients who were affected by a deficit of factor VII ranged between 10,5% and 21%. The other patients were treated locally with tranexamic acid. Results: A total of 50 teeth were extracted, 7 by surgical extraction and 43 by simple extraction. Of the 17 patients included 9 of them suffering from factor VII deficiency, 5 from factor V deficiency, 1 from Glanzmann's thrombasthenia and 2 from Haemophilia A. Pretreatment with recombinant activated factor VII was performed on a total of 8 patients with factor VII deficiency; the remaining 9 patients underwent tranexamic acid treatment. 1 hemorragic postoperative complication was observed. Conclusions: Surgical and no surgical extractions appear to be a safe procedure for patients affected by coagulation disorders when appropriate prophylaxis is adopted.
Keywords
Mouth; Dental diseases; Surgery
Subject
Medicine and Pharmacology, Dentistry and Oral Surgery
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
