Version 1
: Received: 19 April 2022 / Approved: 20 April 2022 / Online: 20 April 2022 (03:42:28 CEST)
How to cite:
Delalande, B.; Tamagawa, H.; Matveev, V. Membrane Potential: The Enigma of Ion Pumps. Preprints2022, 2022040182. https://doi.org/10.20944/preprints202204.0182.v1
Delalande, B.; Tamagawa, H.; Matveev, V. Membrane Potential: The Enigma of Ion Pumps. Preprints 2022, 2022040182. https://doi.org/10.20944/preprints202204.0182.v1
Delalande, B.; Tamagawa, H.; Matveev, V. Membrane Potential: The Enigma of Ion Pumps. Preprints2022, 2022040182. https://doi.org/10.20944/preprints202204.0182.v1
APA Style
Delalande, B., Tamagawa, H., & Matveev, V. (2022). Membrane Potential: The Enigma of Ion Pumps. Preprints. https://doi.org/10.20944/preprints202204.0182.v1
Chicago/Turabian Style
Delalande, B., Hirohisa Tamagawa and Vladimir Matveev. 2022 "Membrane Potential: The Enigma of Ion Pumps" Preprints. https://doi.org/10.20944/preprints202204.0182.v1
Abstract
The generation and maintenance of membrane potential is a fundamental part of Membrane Pump Theory. One of the key points of this hypothesis is based on a natural or facilitated molecular diffusion through several types of ion channels and pumps like the Na/K ATPase. Following the principles of chemistry, electrostatics and geometry, it becomes clear that ion channels cannot function in this way. The ions channels cannot by their location have both a filter function and be ion concentrators, and the Na/K pump by its position in the membrane and by the proposed assumptions is not able to perform its regulatory function. The current model must absolutely be revised according to the current state of our knowledge and allow an advance in the understanding of the phenomena opening new research perspectives.
Biology and Life Sciences, Biochemistry and Molecular Biology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
