Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Tuberculosis among Peoples Who Were Living on the Street and Used Alcohol, Tobacco, and Illegal Drugs: Analysis of Territories in Extreme Vulnerability and Trends in Southern Brazil

Version 1 : Received: 28 March 2022 / Approved: 31 March 2022 / Online: 31 March 2022 (08:05:32 CEST)

A peer-reviewed article of this Preprint also exists.

Scholze, A.R.; Alves, J.D.; Berra, T.Z.; Ramos, A.C.V.; Pieri, F.M.; Pillon, S.C.; Martins, J.T.; Galdino, M.J.Q.; Melo, E.C.; Delpino, F.M.; Tártaro, A.F.; Fronteira, I.; Arcêncio, R.A. Tuberculosis among People Living on the Street and Using Alcohol, Tobacco, and Illegal Drugs: Analysis of Territories in Extreme Vulnerability and Trends in Southern Brazil. Int. J. Environ. Res. Public Health 2022, 19, 7721. Scholze, A.R.; Alves, J.D.; Berra, T.Z.; Ramos, A.C.V.; Pieri, F.M.; Pillon, S.C.; Martins, J.T.; Galdino, M.J.Q.; Melo, E.C.; Delpino, F.M.; Tártaro, A.F.; Fronteira, I.; Arcêncio, R.A. Tuberculosis among People Living on the Street and Using Alcohol, Tobacco, and Illegal Drugs: Analysis of Territories in Extreme Vulnerability and Trends in Southern Brazil. Int. J. Environ. Res. Public Health 2022, 19, 7721.

Abstract

Abstract: (1) Background: tuberculosis presents an epidemiological trend towards inequality, especially among people in social exclusion and situations of vulnerability. To analyze territories where there is a concentration of people diagnosed with tuberculosis, in a street situation, and who make chronic use of alcohol, tobacco, and illicit drugs. We will also analyze trends in this health condition in southern Brazil; (2) Methods: Ecological study, developed in the 399 municipalities of Paraná, Southern Brazil, with all tuberculosis cases in the homeless population registered in the Information System of Notifiable Diseases between 2014 to 2018. For data analysis, we used descriptive statistics, for the time series, the Prais-Winsten autoregression method, whereas for spatial analysis, we used the Getis-Ord Gi technique*; (3) Results: in total, 560 cases were reported. We found a predominance of alcohol, smoking, and illicit drugs users, with an increasing trend in the state and clusters of spatial risk in the East health macro-region; (4) Conclusions: We observed territories with critical levels of highly vulnerable people who use psychoactive substances and are in a street situation. The results highlight the importance of incorporating public policies of social protection to these individuals and resolutive health services that receive and assist in eradicating TB.

Keywords

Tuberculosis; Vulnerable populations; Homeless Persons; Substance-Related Disorders

Subject

Medicine and Pharmacology, Epidemiology and Infectious Diseases

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