Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

COVID-19 Test Frequency Versus Test Sensitivity in Disrupting SARS-CoV-2 Transmission: A Review of Statistical Modeling Simulations

Version 1 : Received: 15 March 2022 / Approved: 25 March 2022 / Online: 25 March 2022 (03:50:14 CET)

How to cite: Rogers, J.; Jackson, L.; Buss, A.; Gawel, S. COVID-19 Test Frequency Versus Test Sensitivity in Disrupting SARS-CoV-2 Transmission: A Review of Statistical Modeling Simulations. Preprints 2022, 2022030338 (doi: 10.20944/preprints202203.0338.v1). Rogers, J.; Jackson, L.; Buss, A.; Gawel, S. COVID-19 Test Frequency Versus Test Sensitivity in Disrupting SARS-CoV-2 Transmission: A Review of Statistical Modeling Simulations. Preprints 2022, 2022030338 (doi: 10.20944/preprints202203.0338.v1).

Abstract

Objectives: This paper presents a statistical review of modelling simulations for frequency and sensitivity of COVID-19 testing paradigms. Methods: We performed a review of preprints and published articles on PubMed from January 1, 2020 – March 1, 2021 using the search terms “COVID screening testing”, “COVID testing frequency”, “COVID testing frequency screening” and “SARS-CoV-2 testing frequency”.Results: Several authors’ conclusions support the claim that test frequency and test sensitivity both play a role in reducing SARS-CoV-2 transmission. We highlight the interplay between frequency of testing, test sensitivity and the speed at which test results are available in our review. Conclusions: Evidence suggests that sensitivity and frequency of testing both play a part in decreasing transmission of disease. We conclude that, overall, test sensitivity plays less of a role in reducing disease transmission in a population compared to the frequency of testing and how quickly test results are available.

Keywords

COVID-19; rapid testing; test sensitivity; test frequency; testing programs; compartmental models

Subject

MATHEMATICS & COMPUTER SCIENCE, Probability and Statistics

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