Potential Clinical Benefits of TDM of Antimicrobials in Japan

Fumiya Ebihara; Yukihiro Hamada; Takumi Maruyama; Toshimi Kimura

doi:10.20944/preprints202201.0277.v1

Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Version 1 : Received: 18 January 2022 / Approved: 19 January 2022 / Online: 19 January 2022 (14:29:36 CET)

Under the Japanese health insurance system, medicines undergoing therapeutic drug monitoring (TDM) can be billed for medical fees if they meet the specified requirements. In Japan, TDM of vancomycin, teicoplanin, aminoglycosides, and voriconazole, which are used for the treatment of infectious diseases, is common practice. This means the levels of antimicrobial agents are measured in-house using chromatography. This review describes personalized medicine based on the use of chromatography as a result of the current situation in Japan.

HPLC; TDM; ceftriaxone; daptomycin; linezolid

Medicine and Pharmacology, Pharmacology and Toxicology

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Potential Clinical Benefits of TDM of Antimicrobials in Japan

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