Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Modulating Visuomotor Sequence Learning by Repetitive Transcranial Magnetic Stimulation: What Do We Know So Far?

Version 1 : Received: 23 November 2021 / Approved: 24 November 2021 / Online: 24 November 2021 (09:18:16 CET)

How to cite: Szucs-Bencze, L.; Vekony, T.; Pesthy, O.; Szabo, N.; Kincses, Z.T.; Turi, Z.; Nemeth, D. Modulating Visuomotor Sequence Learning by Repetitive Transcranial Magnetic Stimulation: What Do We Know So Far?. Preprints 2021, 2021110448 (doi: 10.20944/preprints202111.0448.v1). Szucs-Bencze, L.; Vekony, T.; Pesthy, O.; Szabo, N.; Kincses, Z.T.; Turi, Z.; Nemeth, D. Modulating Visuomotor Sequence Learning by Repetitive Transcranial Magnetic Stimulation: What Do We Know So Far?. Preprints 2021, 2021110448 (doi: 10.20944/preprints202111.0448.v1).

Abstract

Sequence learning and statistical learning are key components of predictive processes and many cognitive, motor, and social skills. The Serial Reaction Time Task (SRTT) can measure this fundamental cognitive process in the visuomotor domain. Repetitive transcranial magnetic stimulation (rTMS) is an increasingly used non-invasive brain stimulation method that can help us to determine the functional role of a given brain region. In this literature review, we systematically analyzed the eligible records (n = 17) that sought to modulate the performance on the SRTT with rTMS. The purpose of the analysis was to determine the effects of the following factors on SRTT performance: (1) stimulated brain areas, (2) rTMS protocols, (3) stimulated hemisphere, (4) timing of the stimulation, (5) SRTT sequence properties, and (6) other methodological features. We found that the two most promising target areas are the primary motor cortex (M1) and the dorsolateral prefrontal cortex (DLPFC). Low-frequency protocols over the M1 usually weakened performance, but the results are less consistent for the DLPFC. Our analysis of these six factors could help design future studies to modulate sequence learning by non-invasive brain stimulation.

Keywords

non-invasive brain stimulation; sequence learning; statistical learning; repetitive TMS; DLPFC

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our diversity statement.

Leave a public comment
Send a private comment to the author(s)
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.