Version 1
: Received: 16 April 2021 / Approved: 19 April 2021 / Online: 19 April 2021 (12:53:01 CEST)
How to cite:
Rodríguez Martín, B.; Fernandez Rodríguez, E.J.; Sánchez Gómez, C.; Cruz Hernandez, J.J.; Rihuete Galve, M.I. Study of How Clinical and Sociodemographic Variables Influence Chemotherapy-induced Cognitive Deterioration in Women with Breast Cancer. Preprints2021, 2021040480. https://doi.org/10.20944/preprints202104.0480.v1
Rodríguez Martín, B.; Fernandez Rodríguez, E.J.; Sánchez Gómez, C.; Cruz Hernandez, J.J.; Rihuete Galve, M.I. Study of How Clinical and Sociodemographic Variables Influence Chemotherapy-induced Cognitive Deterioration in Women with Breast Cancer. Preprints 2021, 2021040480. https://doi.org/10.20944/preprints202104.0480.v1
Rodríguez Martín, B.; Fernandez Rodríguez, E.J.; Sánchez Gómez, C.; Cruz Hernandez, J.J.; Rihuete Galve, M.I. Study of How Clinical and Sociodemographic Variables Influence Chemotherapy-induced Cognitive Deterioration in Women with Breast Cancer. Preprints2021, 2021040480. https://doi.org/10.20944/preprints202104.0480.v1
APA Style
Rodríguez Martín, B., Fernandez Rodríguez, E.J., Sánchez Gómez, C., Cruz Hernandez, J.J., & Rihuete Galve, M.I. (2021). Study of How Clinical and Sociodemographic Variables Influence Chemotherapy-induced Cognitive Deterioration in Women with Breast Cancer. Preprints. https://doi.org/10.20944/preprints202104.0480.v1
Chicago/Turabian Style
Rodríguez Martín, B., Juan Jesus Cruz Hernandez and María Isabel Rihuete Galve. 2021 "Study of How Clinical and Sociodemographic Variables Influence Chemotherapy-induced Cognitive Deterioration in Women with Breast Cancer" Preprints. https://doi.org/10.20944/preprints202104.0480.v1
Abstract
Background: Of the many side effects suffered by cancer patients, those related to cognitive performance have become increasingly prominent in clinical practice. We know that chemotherapy generates a series of side effects, such as nausea and vomiting, alopecia, and so on, which can be counteracted by complementary medication. However, in the case of post-chemotherapy cognitive impairment, or chemo brain, these cannot be controlled with drug therapies. However, before any intervention can be considered, it is necessary to know exactly what cognitive impairment is being triggered. For this reason, we decided to study the cognitive status of breast cancer patients. Methods: analytical, prospective, three-measure longitudinal, intrasubject unifactorial, non-probabilistic and accidental assignment study. The sample came from the Medical Oncology Department at Hospital de Salamanca, in Spain. Cognitive function (Trail Making Test and Stroop Test) was established as the primary variable; the presence of sleep disorders (Insomnia Severity Index, ISI) and anaemia (haemoglobin levels in blood) were analysed as secondary variables, in addition to intervening variables (age, stage, type of carcinoma, radiotherapy, menopause, social support network, marital status, years of schooling and employment status). Results: We recruited 151 individuals according to the selection criteria. We can confirm that factors including anaemia, menopause, patient support network and marital status, years of schooling, and employment status did affect the cognitive performance of the patients in the study. In contrast, sleep disorders, age, radiotherapy treatment, stage of disease, and type of carcinoma did not affect the cognitive performance of the cancer patients. Conclusions: Chemotherapy does impact the cognitive performance of breast cancer patients.
Keywords
Chemobrain; Cancer; Cognitive function; Insomnia.
Subject
Medicine and Pharmacology, Immunology and Allergy
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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