Lee, D.-H.; Helal, Z.H.; Kim, J.; Hunt, A.; Barbieri, A.; Tocco, N.; Frasca, S., Jr.; Kerr, K.; Hyeon, J.-Y.; Chung, D.H.; Risatti, G. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in a Dog in Connecticut in February 2021. Viruses2021, 13, 2141.
Lee, D.-H.; Helal, Z.H.; Kim, J.; Hunt, A.; Barbieri, A.; Tocco, N.; Frasca, S., Jr.; Kerr, K.; Hyeon, J.-Y.; Chung, D.H.; Risatti, G. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in a Dog in Connecticut in February 2021. Viruses 2021, 13, 2141.
Lee, D.-H.; Helal, Z.H.; Kim, J.; Hunt, A.; Barbieri, A.; Tocco, N.; Frasca, S., Jr.; Kerr, K.; Hyeon, J.-Y.; Chung, D.H.; Risatti, G. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in a Dog in Connecticut in February 2021. Viruses2021, 13, 2141.
Lee, D.-H.; Helal, Z.H.; Kim, J.; Hunt, A.; Barbieri, A.; Tocco, N.; Frasca, S., Jr.; Kerr, K.; Hyeon, J.-Y.; Chung, D.H.; Risatti, G. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in a Dog in Connecticut in February 2021. Viruses 2021, 13, 2141.
Abstract
We report the first detection of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus from a dog in Connecticut during February 2021. Complete genome sequencing and phylo-genetic analysis of the hCoV-19/USA/CT-CVMDL-Dog-1/2021 (CT_Dog/2021) virus were con-ducted to identify the origin and lineage of the virus. The CT_Dog/2021 virus belonged to the GH/B1.2. genetic lineage and was genetically close to SARS-CoV-2 identified from humans in the U.S. during the winter of 2020-2021. However, it was not related to other SARS-CoV-2 identified from companion animals in the U.S. It contained both D614G in spike and P323L in nsp12 substitutions which have become the dominant mutations in the United States. The continued sporadic detections of SARS-CoV-2 in companion animals warrant public health concerns about their potential to become a new reservoir species of SARS-CoV-2.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
