Version 1
: Received: 22 September 2020 / Approved: 24 September 2020 / Online: 24 September 2020 (08:13:15 CEST)
How to cite:
Wu, J.; Zha, P. Clinical Trials and Reductionist Approach Preclude Cures for Chronic Diseases Due to Flawed Presumptions. Preprints2020, 2020090572. https://doi.org/10.20944/preprints202009.0572.v1
Wu, J.; Zha, P. Clinical Trials and Reductionist Approach Preclude Cures for Chronic Diseases Due to Flawed Presumptions. Preprints 2020, 2020090572. https://doi.org/10.20944/preprints202009.0572.v1
Wu, J.; Zha, P. Clinical Trials and Reductionist Approach Preclude Cures for Chronic Diseases Due to Flawed Presumptions. Preprints2020, 2020090572. https://doi.org/10.20944/preprints202009.0572.v1
APA Style
Wu, J., & Zha, P. (2020). <b>Clinical Trials and Reductionist Approach Preclude Cures for Chronic Diseases </b><b>Due to Flawed </b><b>Presumptions</b>. Preprints. https://doi.org/10.20944/preprints202009.0572.v1
Chicago/Turabian Style
Wu, J. and Ping Zha. 2020 "<b>Clinical Trials and Reductionist Approach Preclude Cures for Chronic Diseases </b><b>Due to Flawed </b><b>Presumptions</b>" Preprints. https://doi.org/10.20944/preprints202009.0572.v1
Abstract
Modern medicine adopted four presumptions when it evolved from ancient experienced-based mind-body medicine. To understand its failure in finding cures for chronic diseases, we examined four presumptions, and found that statistical population of health properties does not exist for most research purposes, mathematical models are misused to model intensive properties, synthetic drugs are inherently more dangerous than nature-made medicines under their respective application conditions, and reductionist treatments are inferior and inherently dangerous. We found that clinical trials are valid only for research where treatment effect is much stronger than the total effects of all interfering or co-causal factors or errors introduced by misused mathematical models can be tolerated. In all other situations, clinical trials introduce excessive errors and fail to detect treatment effects, or produce biased, incorrect or wrong results. We further found that chronic diseases are manifestation of small departures in multiple process attributes in distinctive personal biological pathways networks, that modern medicine lacks required accuracy for accurately characterizing chronic diseases, and that reductionist treatments are good at controlling symptoms and safe for short term uses. For all stated reasons, as long as modern medicine continues relying on the flawed presumptions, it can never find predictable cures for chronic diseases. By implication, predictable cures to chronic diseases are adjustments to lifestyle, dietary, emotional, and environmental factors to slowly correct departures in process attributes responsible for chronic diseases.
randomized controlled clinical trials; mathematical model; binary system; statistical analysis; epidemiological model; junk science; reductionist treatments; failure of medicine
Subject
Medicine and Pharmacology, Other
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
