Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

A case of Miller fisher’s Syndrome Presenting with Dysphagia and Nasal Voice

Version 1 : Received: 29 August 2020 / Approved: 30 August 2020 / Online: 30 August 2020 (14:41:29 CEST)

How to cite: Tamaoui, L.; Rahmani, M.; Touati, H.; Errguig, L.; Benabdeljlil, M.; Aidi, S. A case of Miller fisher’s Syndrome Presenting with Dysphagia and Nasal Voice. Preprints 2020, 2020080669 (doi: 10.20944/preprints202008.0669.v1). Tamaoui, L.; Rahmani, M.; Touati, H.; Errguig, L.; Benabdeljlil, M.; Aidi, S. A case of Miller fisher’s Syndrome Presenting with Dysphagia and Nasal Voice. Preprints 2020, 2020080669 (doi: 10.20944/preprints202008.0669.v1).

Abstract

Miller Fisher Syndrome (MFS) is a rare variant of Guillain-Barré Syndrome (GBS). It is largely a clinical diagnosis based on the classical features of ataxia, areflexia, and opthalmoplegia. Its clinical evolution is most often favorable. However, other neurological signs and symptoms may also be present. Supportive laboratory studies (positivity of antibodies, CSF albumin-cytological dissociation and nerve conduction studies) are useful especially in uncommon presentations. We report a case of a 74-year-old patient who exhibited dysphonia and difficulty to swallowing previously to the classic triad of ataxia, areflexia, and opthalmoplegia, characteristic of MFS. CSF analysis demonstrates an albumin-cytological dissociation but anti-GQ1b antibody were negative. The patient has spontaneously and completely recovered after several weeks.

Subject Areas

Miller Fisher Syndrome; Guillain Barré Syndrome variant; Dysphonia; Dysphagia

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