Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

A case of Miller fisher’s Syndrome Presenting with Dysphagia and Nasal Voice

Version 1 : Received: 29 August 2020 / Approved: 30 August 2020 / Online: 30 August 2020 (14:41:29 CEST)

A peer-reviewed article of this Preprint also exists.

TAMAOUI, L.; RAHMANI, M.; TOUATI, H.; ERRGUIG, L.; BENABDELJLIL, M.; AIDI, S. Pharyngo-Cervico-Brachial Variant of Guillain-Barré or Miller Fisher Syndromes? When the Overlap Is Misleading. Reports 2020, 3, 34. TAMAOUI, L.; RAHMANI, M.; TOUATI, H.; ERRGUIG, L.; BENABDELJLIL, M.; AIDI, S. Pharyngo-Cervico-Brachial Variant of Guillain-Barré or Miller Fisher Syndromes? When the Overlap Is Misleading. Reports 2020, 3, 34.

Journal reference: Reports 2020, 3, 34
DOI: 10.3390/reports3040034

Abstract

Miller Fisher Syndrome (MFS) is a rare variant of Guillain-Barré Syndrome (GBS). It is largely a clinical diagnosis based on the classical features of ataxia, areflexia, and opthalmoplegia. Its clinical evolution is most often favorable. However, other neurological signs and symptoms may also be present. Supportive laboratory studies (positivity of antibodies, CSF albumin-cytological dissociation and nerve conduction studies) are useful especially in uncommon presentations. We report a case of a 74-year-old patient who exhibited dysphonia and difficulty to swallowing previously to the classic triad of ataxia, areflexia, and opthalmoplegia, characteristic of MFS. CSF analysis demonstrates an albumin-cytological dissociation but anti-GQ1b antibody were negative. The patient has spontaneously and completely recovered after several weeks.

Keywords

Miller Fisher Syndrome; Guillain Barré Syndrome variant; Dysphonia; Dysphagia

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