Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Long-Term Effects of Kasai Portoenterostomy for Biliary Atresia

Version 1 : Received: 30 July 2020 / Approved: 7 August 2020 / Online: 7 August 2020 (09:27:14 CEST)

A peer-reviewed article of this Preprint also exists.

Degtyareva, A.; Razumovskiy, A.; Kulikova, N.; Ratnikov, S.; Filippova, E.; Gordeeva, E.; Albegova, M.; Rebrikov, D.; Puchkova, A. Long-Term Effects of Kasai Portoenterostomy for Biliary Atresia Treatment in Russia. Diagnostics 2020, 10, 686. Degtyareva, A.; Razumovskiy, A.; Kulikova, N.; Ratnikov, S.; Filippova, E.; Gordeeva, E.; Albegova, M.; Rebrikov, D.; Puchkova, A. Long-Term Effects of Kasai Portoenterostomy for Biliary Atresia Treatment in Russia. Diagnostics 2020, 10, 686.

Abstract

The prospective study enrolled 144 patients after surgical treatment of biliary atresia in early infancy. We analyze the immediate effectiveness of the surgery and the age-related structure of complications in the up to 16-year follow-up. The immediate 2-year survival rate after the surgery constituted 49.5%. At the time of this writing, 17 of the patients have celebrated their 10th birthdays with good quality of life and no indications for LT. The obtained results underscore the critical importance of surgical correction of BA by Kasai surgery during the first 60 days of life and subsequent dynamic follow-up of the patients for the purpose of the early detection and timely correction of possible complications.

Keywords

biliary atresia; Kasai portoenterostomy; cholangitis; portal hypertension; bile ducts dilatations; native liver survival

Subject

Medicine and Pharmacology, Pediatrics, Perinatology and Child Health

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