Working Paper Review Version 1 This version is not peer-reviewed

Bioartificial Pancreas with Tapered Conduits for Diabetes Management

Version 1 : Received: 6 June 2020 / Approved: 7 June 2020 / Online: 7 June 2020 (14:19:28 CEST)

How to cite: Wang, T. Bioartificial Pancreas with Tapered Conduits for Diabetes Management. Preprints 2020, 2020060088 Wang, T. Bioartificial Pancreas with Tapered Conduits for Diabetes Management. Preprints 2020, 2020060088

Abstract

Diabetes is a life-long illness, it requires life-long solution. Today’s treatment is trading one type of pain with another, never truly ride off the illness. When Artificial Pancreas (AP) offered a possibility of cure, it stirred up a great deal of interest in the diabetic community (1). The system was based on artificial intelligence. It can automate the dosing of insulin to reduce high blood sugar levels overnight. The most dangerous time for diabetes. Artificial Pancreas may be able to allow diabetic patients to sleep through the night without waking up to check and manage their blood glucose levels. It was a significant advancement. However, the achievement was limited: 76.4% in range with the system vs. 67.8% without the system. This accomplishment was creditable, but not optimal. If Artificial Pancreas was to be offered as a viable treatment for diabetes, it must be a life-long solution and must be a total solution. Artificial Pancreas has failed in this challenge. We decided to pursue an alternative approach, a self-regulated system: bioartificial pancreas. It has the potential became a complete cure.

Subject Areas

Diabetes; Islets; Encapsulation; Bioartificial Pancreas; tapered conduit

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