Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

A First Review to Explore the Association of Air Pollution (PM and NO2) on Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2)

Version 1 : Received: 13 May 2020 / Approved: 18 May 2020 / Online: 18 May 2020 (09:36:25 CEST)

How to cite: Copat, C.; Cristaldi, A.; Fiore, M.; Grasso, A.; Zuccarello, P.; Oliveri Conti, G.; Signorelli, S.S.; Ferrante, M. A First Review to Explore the Association of Air Pollution (PM and NO2) on Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2). Preprints 2020, 2020050299. https://doi.org/10.20944/preprints202005.0299.v1 Copat, C.; Cristaldi, A.; Fiore, M.; Grasso, A.; Zuccarello, P.; Oliveri Conti, G.; Signorelli, S.S.; Ferrante, M. A First Review to Explore the Association of Air Pollution (PM and NO2) on Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2). Preprints 2020, 2020050299. https://doi.org/10.20944/preprints202005.0299.v1

Abstract

A new coronavirus (SARS-CoV-2) have determined a pneumonia outbreak in China (Wuhan and Hubei) on December 2019. While pharmaceutical and non-pharmaceutical intervention strategies are strengthened worldwide, the scientific community has been studying the risk factors associated with SARS-Cov-2, to enrich epidemiological information. For a long time, before the industrialized era, air pollution has been a real and big health concern and it is today a very serious environmental risk for many diseases and anticipated deaths in the world. It has long been known that air pollutants increasing the invasiveness of pathogens for humans by acting as a carrier and making people more sensitive to pathogens through a negative influence on the immune system. Based on scientific evidences, the hypothesis that air pollution, resulting from a combination of factors such as meteorological data, level of industrialization as well as regional topography, can acts both as an infection carrier as a harmful factor of the health outcomes of COVID-19 disease has been raised recently. This hypothesis is turning in scientific evidence, thanks to the numerous studies that have been launched all over the world. With this review, we want to provide a first unique view of all the first epidemiological studies relating the association between air pollution and SARS-CoV-2. Major findings are consistent, highlighting the important contribution of air pollution on the COVID-19 spread and with a less extent also PM10.

Keywords

air pollution; particulate matter; nitrogen dioxide; COVID-19; pandemic

Subject

Medicine and Pharmacology, Epidemiology and Infectious Diseases

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