Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Liver Disease - A Concern in SARS-COV2 Infection

Version 1 : Received: 6 May 2020 / Approved: 7 May 2020 / Online: 7 May 2020 (08:57:14 CEST)

How to cite: Mondal, P.; Dogra, S. Liver Disease - A Concern in SARS-COV2 Infection. Preprints 2020, 2020050114 (doi: 10.20944/preprints202005.0114.v1). Mondal, P.; Dogra, S. Liver Disease - A Concern in SARS-COV2 Infection. Preprints 2020, 2020050114 (doi: 10.20944/preprints202005.0114.v1).

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of coronavirus disease (COVID-19) that has resulted in a global pandemic. The clinical symptoms of the disease vary from mild illness to acute respiratory issues. Older age, diabetes, cardiac diseases predict poor prognosis in COVID-19 patients. Various reports mention the incidence of liver injury with transient elevations in the levels of aminotransferases (liver function enzymes). The clinical characteristics, etiology and underlying pathophysiological mechanisms associated with liver damage in SARS-CoV2 infected patients need to be explored. This review highlights the severity of the hepatic injury in COVID-19.

Subject Areas

COVID19; ACE2; diabetes; SARS-CoV2; liver injury

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