Preprint Review Version 1 This version is not peer-reviewed

Non-Dental Drugs A Dentist Should Know: A Review

Version 1 : Received: 1 May 2020 / Approved: 2 May 2020 / Online: 2 May 2020 (11:50:24 CEST)

How to cite: Saleem, K.; Ahmad, P.; Karobari, M.I.; Kamal, M.A.; Asif, J.A.; Noorani, T.Y. Non-Dental Drugs A Dentist Should Know: A Review. Preprints 2020, 2020050003 (doi: 10.20944/preprints202005.0003.v1). Saleem, K.; Ahmad, P.; Karobari, M.I.; Kamal, M.A.; Asif, J.A.; Noorani, T.Y. Non-Dental Drugs A Dentist Should Know: A Review. Preprints 2020, 2020050003 (doi: 10.20944/preprints202005.0003.v1).

Abstract

More than 15,000 prescriptions and over the counter drugs are available according to the US Food and Drug Administration website. Moreover, several herbal medicines and dietary supplements are readily available to add to the list of possible drugs, which can potentially cause adverse drug interactions. These are a pressing concern for all as they can interfere with many dental procedures. Additionally, the number of geriatric patients seen in routine dental practice has increased over time. This implies that there are more patients with multiple diseases and health conditions like hypertension, diabetes, problems associated with the cardiovascular, renal and gastrointestinal systems, arthritis, osteoporosis, etc. All these require patients to be on certain medications. Furthermore, advancement in the dental field has led to more complex dental procedures (implants, grafts) being carried out in a general dental practice. These advanced and slightly more invasive treatments require the use of certain drugs before, during and after the treatment like local anesthetics, vasoconstrictors, anxiolytics, analgesics and antibiotics. All of these can possibly interact with medications a patient is already taking and can also interfere with the current dental treatment and create complications. This article aims to provide necessary information about commonly encountered systemic diseases and associated treating medications, their mechanism of action, possible complications and their management. The classes of drugs discussed include anti-platelet agents, vitamin K antagonists, novel oral anticoagulants, bisphosphonates, disease-modifying anti-rheumatic drugs and oral contraceptives.

Subject Areas

Anti-platelets; Anti-rheumatic drugs; Bisphosphonates; Oral anticoagulants; Oral contraceptives; Vitamin K antagonist

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