Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Neurological Manifestations and Complications of COVID-19: A Literature Review

Version 1 : Received: 23 April 2020 / Approved: 25 April 2020 / Online: 25 April 2020 (02:36:21 CEST)

How to cite: Ahmad, I.; Rathore, F.A. Neurological Manifestations and Complications of COVID-19: A Literature Review. Preprints 2020, 2020040453 (doi: 10.20944/preprints202004.0453.v1). Ahmad, I.; Rathore, F.A. Neurological Manifestations and Complications of COVID-19: A Literature Review. Preprints 2020, 2020040453 (doi: 10.20944/preprints202004.0453.v1).

Abstract

The Coronavirus disease due to SARS-CoV-2 emerged in Wuhan city, China in December 2019 and rapidly spread more than 200 countries as a global health pandemic. There are more 3 million confirmed cases and around 207,000 fatalities. The primary manifestation is respiratory and cardiac but neurological manifestations are being reported in the literature as case reports and case series. The most common reported symptoms to include headache and dizziness followed by encephalopathy and delirium. Among the complications noted are Cerebrovascular accident, Guillian barre syndrome, acute transverse myelitis, and acute encephalitis. The most common peripheral manifestation was hyposmia. It is further noted that sometimes the neurological manifestations can precede the typical features like fever and cough and later on typical manifestations develop in these patients. Hence a high index of suspicion is required for timely diagnosis and isolation of cases to prevent the spread in neurology wards. We present a narrative review of the neurological manifestations and complications of COVID-19. Our aim is to update the neurologists and physicians working with suspected cases of COVID-19 about the possible neurological presentations and the probable neurological complications resulting from this novel virus infection.

Subject Areas

neurology; clinical features; coronavirus; stroke; encephalitis; headache; delirium

Comments (2)

Comment 1
Received: 2 May 2020
Commenter: Salman Mansoor
The commenter has declared there is no conflict of interests.
Comment: I have read your article and shared it with my colleagues in our department here for further discussion. I think this was a very timely review and you went really thorough. I wish you best of luck with its publication. Regards, Dr Salman Mansoor MBBS, MRCPI, FEBN, FCPS-Trained (Neurology) Registrar Neurology, Department of Neurology, Sligo University Hospital, Ireland
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Response 1 to Comment 1
Received: 5 May 2020
Commenter: Farooq Azam Rathore (Click to see Publons profile: )
The commenter has declared there is no conflict of interests.
Comment: Thank You for your appreciation. The manuscript has been accepted for publication in the Journal of Clinical Neuroscience as well. Please check their website after one week for the final manuscript

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