Working Paper Case Report Version 1 This version is not peer-reviewed

Novel Coronavirus Infection and Acute Kidney Injury in Two Renal Transplant Recipients: Case Report

Version 1 : Received: 11 March 2020 / Approved: 12 March 2020 / Online: 12 March 2020 (03:02:03 CET)

How to cite: Li, Q.; Cheng, Q.; Zhao, Z.; Zeng, L.; Zhu, L.; Guo, W.; Li, C.; Wang, J.; Li, S.; Shen, N.; Ge, Q. Novel Coronavirus Infection and Acute Kidney Injury in Two Renal Transplant Recipients: Case Report. Preprints 2020, 2020030190 Li, Q.; Cheng, Q.; Zhao, Z.; Zeng, L.; Zhu, L.; Guo, W.; Li, C.; Wang, J.; Li, S.; Shen, N.; Ge, Q. Novel Coronavirus Infection and Acute Kidney Injury in Two Renal Transplant Recipients: Case Report. Preprints 2020, 2020030190

Abstract

Novel coronavirus infection is a recent infective agent that causes severe potentially fatal pneumonia. The clinical presentation includes asymptomatic infection, severe pneumonia, and acute respiratory failure. Data pertaining to the clinical presentation of solid organ transplant recipients are scarce. Two cases of novel coronavirus infection in two recipients of renal transplant with variable clinical presentations and outcomes are reported. The first patient presented with progressive respiratory symptoms, acute renal failure, and passed away, whereas the second one, although presented with respiratory tract symptoms and hypoxemia remained stable and exhibited an excellent clinical recovery despite recent reception of thymoglobulin induction. This paper reports rare cases of novel coronavirus infection in renal transplant recipients. For an enhanced insight of the novel coronavirus infection and acute kidney injury on the clinical presentation, severity, and outcome in solid organ transplant recipients, further investigations are required.

Subject Areas

novel coronavirus infection; renal transplant; acute kidney injury

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