Preprint Review Version 1 This version is not peer-reviewed

Controlling Systemic Inflammation by Careful Formulation of Topical Skin Care Products: Our Bodies Didn’t Evolve With All the Current Chemicals in Skin Care Products

Version 1 : Received: 21 February 2020 / Approved: 25 February 2020 / Online: 25 February 2020 (05:23:17 CET)

How to cite: Maguire, G. Controlling Systemic Inflammation by Careful Formulation of Topical Skin Care Products: Our Bodies Didn’t Evolve With All the Current Chemicals in Skin Care Products. Preprints 2020, 2020020360 (doi: 10.20944/preprints202002.0360.v1). Maguire, G. Controlling Systemic Inflammation by Careful Formulation of Topical Skin Care Products: Our Bodies Didn’t Evolve With All the Current Chemicals in Skin Care Products. Preprints 2020, 2020020360 (doi: 10.20944/preprints202002.0360.v1).

Abstract

Although man is still rapidly evolving, he has not co-evolved with all of the modern chemicals made by man, including those in cosmetic products. Care must be taken when formulating products so that commonly used ingredients, such as polyethylene glycol, can be substituted with safer ingredients to which man has adapted and that will not cause irritation and inflammation. This is especially important given that induction of skin inflammation will cause systemic inflammation. A review of the literature and of commercially available products was made to highlight techniques and products that remediate inflammation or induce inflammation. Many skin care products contain chemicals that induce irritation and inflammation that may lead to chronic, systemic inflammation. Well studied natural products, especially skin identical chemicals, may offer an advantage compared to recent man-made chemicals in cosmetic and topical formulations and help to reduce skin inflammation as well as skin derived systemic chronic inflammation.

Subject Areas

skin care; topicals; toxicity; ingredients; systemic inflammation

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