Preprint Article Version 1 This version is not peer-reviewed

Relationships between Urine Albumin Excretion and Dietary Habits in Patients with Type 2 Diabetes

Version 1 : Received: 29 June 2019 / Approved: 8 July 2019 / Online: 8 July 2019 (14:44:24 CEST)

How to cite: Matsui, S.; Someya, Y.; Yoshida, H. Relationships between Urine Albumin Excretion and Dietary Habits in Patients with Type 2 Diabetes. Preprints 2019, 2019070092 (doi: 10.20944/preprints201907.0092.v1). Matsui, S.; Someya, Y.; Yoshida, H. Relationships between Urine Albumin Excretion and Dietary Habits in Patients with Type 2 Diabetes. Preprints 2019, 2019070092 (doi: 10.20944/preprints201907.0092.v1).

Abstract

Background: The dietary factors and nutrients contributing to the prevention of microalbuminuria in type 2 diabetic nephropathy is unclear, so we investigated dietary factors affecting urinary albumin excretion in patients with type 2 diabetes. Methods: 42 patients with type 2 diabetes were participated, the subjects were divided to a normal albuminuria group (urinary albumin / creatinine ratio of less than 30 mg / g Cr) and a microalbuminuria group of 30 mg / g to 299 mg / g Cr. We performed casual blood sampling and conducted a food frequency questionnaire survey. Results: There were no significant differences in age, BMI and other physiological and biochemical data, the average daily intake of energy and many of nutrients, while β-cryptoxanthin was significantly lower in the microalbuminuria group than in the normal group (506.4 ± 793.9 μg/day vs. 715.3 ± 500.3 μg/day, p <0.05). The intake of 17 food groups per day showed that the intakes of fruits were significantly lower in the microalbuminuria group than in the normal group (76.9 ± 134.1 g vs. 111.9 ± 84.5 g, p <0.05). Conclusion: These results suggest that fruits and foods rich in β-cryptoxanthin would make it possible to prevent diabetic nephropathy progression.

Subject Areas

Type 2 diabetes; urea albumin excretion; food frequency questionnaire survey; β-cryptoxanthin; fruits

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