Preprint Article Version 1 This version is not peer-reviewed

Characteristics of Fever and Response to Antipyretic Therapy in Military Personnel with Adenovirus Positive Community-Acquired Pneumonia

Version 1 : Received: 2 June 2019 / Approved: 3 June 2019 / Online: 3 June 2019 (14:02:51 CEST)

How to cite: Park, C. Characteristics of Fever and Response to Antipyretic Therapy in Military Personnel with Adenovirus Positive Community-Acquired Pneumonia. Preprints 2019, 2019060024 (doi: 10.20944/preprints201906.0024.v1). Park, C. Characteristics of Fever and Response to Antipyretic Therapy in Military Personnel with Adenovirus Positive Community-Acquired Pneumonia. Preprints 2019, 2019060024 (doi: 10.20944/preprints201906.0024.v1).

Abstract

In 2014, the outbreak of adenoviral pneumonia occurred in Korean military training center. However, there is limited data on characteristics of fever and its response to antipyretics therapy in immunocompetent adults with adenoviral positive community-acquired pneumonia (CAP). Medical records of patients who were admitted to Armed Forces Chuncheon Hospital for treatment of CAP between January 2014 and December 2016 were retrospectively analyzed. We evaluated demographics, clinico-laboratory findings and radiologic findings at admission were compared between adenovirus positive (Adv) group and adenovirus negative (non-Adv) group. Out of 251 military personnel with CAP during the study periods, 67 were classified into Adv group while 184 were Non-Adv group. Patients with Adv group had a longer duration of fever after admission and symptom onset. Adv group patients had a higher mean temperature at admission and more observed over 40 and 39 to 40℃. Adv group patients had more commonly observed no response to antipyretic treatment and adverse events after antipyretics use. Length of hospital stay had no significant difference between two groups and no patient died in both groups. In our study, Adv positive CAP in patients with immunocompetent military personnel had distinct characteristics of fever and response to antipyretic treatment.

Subject Areas

adenovirus; pneumonia; fever; response to antipyretic treatment

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