Preprint Article Version 1 This version is not peer-reviewed

Quantum Modeling: A Bridge between the Pumping and Signaling Functions of the Na/K – ATPase

Version 1 : Received: 11 July 2018 / Approved: 12 July 2018 / Online: 12 July 2018 (05:26:21 CEST)

A peer-reviewed article of this Preprint also exists.

Wang, W.; Shapiro, J.I. Quantum Modeling: A Bridge between the Pumping and Signaling Functions of Na/K-ATPase. Int. J. Mol. Sci. 2018, 19, 2347. Wang, W.; Shapiro, J.I. Quantum Modeling: A Bridge between the Pumping and Signaling Functions of Na/K-ATPase. Int. J. Mol. Sci. 2018, 19, 2347.

Journal reference: Int. J. Mol. Sci. 2018, 19, 2347
DOI: 10.3390/ijms19082347

Abstract

Although the signaling function of Na/K ATPase is been studied for decades, the chasm between the pumping function and the signaling function of Na/K – ATPase is still an open issue.  This article explores the relationship between ion pumping and signaling with attention to the amplification of oxidants through this signaling function. Starting with some experimental observations published by our laboratories and others, we develop some predictions regarding cellular oxidant stress.

Subject Areas

Na/K – ATPase; Markov chain; master equation; Src; oxidant stress; reactive oxygen species; aging

Readers' Comments and Ratings (0)

Leave a public comment
Send a private comment to the author(s)
Rate this article
Views 0
Downloads 0
Comments 0
Metrics 0
Leave a public comment

×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.