Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Medication-related burden among patients with chronic disease conditions: perspectives of patients attending non-communicable disease clinics in a primary healthcare setting in Qatar

Version 1 : Received: 25 June 2018 / Approved: 25 June 2018 / Online: 25 June 2018 (14:35:31 CEST)

A peer-reviewed article of this Preprint also exists.

Zidan, A.; Awisu, A.; El-Hajj, M.S.; Al-Abdulla, S.A.; Figueroa, D.C.R.; Kheir, N. Medication-Related Burden among Patients with Chronic Disease Conditions: Perspectives of Patients Attending Non-Communicable Disease Clinics in a Primary Healthcare Setting in Qatar. Pharmacy 2018, 6, 85. Zidan, A.; Awisu, A.; El-Hajj, M.S.; Al-Abdulla, S.A.; Figueroa, D.C.R.; Kheir, N. Medication-Related Burden among Patients with Chronic Disease Conditions: Perspectives of Patients Attending Non-Communicable Disease Clinics in a Primary Healthcare Setting in Qatar. Pharmacy 2018, 6, 85.

Abstract

The aim of this cross-sectional study was to assess the perceived medication-related burden among patients with multiple non-communicable diseases (NCDs), and to investigate the association between perceived burden and adherence to medication therapy. Medication-related burden was measured in three primary care clinics in Qatar using the Living with Medicines Questionnaire (LMQ) among adults with diabetes, with or without other comorbidities. Adherence was measured using the Adherence to Refills and Medications Scale (ARMS). Two hundred ninety-three eligible patients participated in the study. Majority of participants reported experiencing minimum (66.6%) to moderate (24.1%) medication-related burden. There was a significant positive correlation between the medication-related burden (measured by the LWQ) and medication adherence (measured by ARMS) (rs (253) = 0.317, p <0.0005). The duration of diabetes diagnosis, adherence score, marital status, employment status, and presence diagnosis of hypertension were significant predictors of medication burden. A considerable proportion of the patients in this study have reported experiencing medication-related burden. Healthcare providers should seek strategies to address this burden especially among patients with risk factors of cardiovascular diseases, non-adherent to their medication therapy, living alone, or non-employed.

Keywords

Medication-related burden; Questionnaire; chronic disease conditions; adherence

Subject

Medicine and Pharmacology, Medicine and Pharmacology

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