Submitted:
16 July 2025
Posted:
17 July 2025
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Abstract
Keywords:
Introduction
Method
Research Design and Subjects
Data Collection
Statistical Analysis
Results
Discussion
Conclusion
Contributions
Funding
Conflicts of Interest
List of Abbreviations:
References
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| Variable | non PS-UI | PS-UI | p - value | ||
|---|---|---|---|---|---|
| Partnership status | Married | 311 (83.4%) | 515 (83.6%) | 0.926 | |
| Not married | 62 (16.6%) | 101 (16.4%) | |||
| Education level | basic level | 27 (7.2%) | 42 (6.9%) | 0.014 | |
| high school | 229 (61.1%) | 427 (69.7%) | |||
| college/university | 119 (31.7%) | 144 (23.5%) | |||
| Ethnicity | Caucasian | 299 (81%) | 495 (80.5%) | 0.835 | |
| Non-caucasian | 70 (19%) | 120 (19.5%) | |||
| Pregestational BMI (kg/m2) | 26.9 ± 6.25 | 28.48 ± 7.28 | 0.002 | ||
| BMI - 1st TP (kg/m2) | 29.4 ± 6.04 | 30.8 ± 6.85 | 0.004 | ||
| BMI - 2nd TP (kg/m2) | 31.6 ± 6.20 | 33.75 ± 6.51 | 0.002 | ||
| Gestational weight gain - 1st TP (kg) | 6.39 ± 5.04 | 6.08 ± 6.19 | 0.477 | ||
| Gestational weight gain - 2nd TP (kg) | 11.76 ± 7.34 | 11.36 ± 7.63 | 0.613 | ||
| Fasting blood glucose (mg/dL) | 79.48 ± 12.71 | 80.11 ± 14.44 | 0.583 | ||
| OGTT - fasting (mg/dL) | 74.82 ± 12.66 | 76.11 ± 11.06 | 0.161 | ||
| OGTT- 1 h (mg/dL) | 116.7 ± 31.27 | 119.17 ± 32.7 | 0.321 | ||
| OGTT - 2 h (mg/dL) | 105.08 ± 28.1 | 107.01± 8.88 | 0.378 | ||
| Chronic coughing | 0 | 9 (1.8%) | 0.025 | ||
| Constipation | 91 (31.5%) | 152 (28.9%) | 0.439 | ||
| Fecal incontinence | 3 (1.1%) | 6 (1.2%) | 0.887 | ||
| Previous arterial hypertension | 24 (8.3%) | 53 (10.2%) | 0.376 | ||
| Alcohol consumption | 1 (0.4%) | 9 (1.8%) | 0.091 | ||
| Smoking in pregnancy | 12 (4.3%) | 26 (5%) | 0.615 | ||
| Physical activity | 66 (23.1%) | 76 (14.7%) | 0.003 | ||
| Gestational diabetes mellitus | 81 (22%) | 154 (25.2%) | 0.242 | ||
| Pregnancy-induced hypertension | 2 (3%) | 8 (4.4%) | 0.611 | ||
| Urinary tract infection | 7 (10.8%) | 22 (12.4%) | 0.735 | ||
| Weeks of gestation | ||||
|---|---|---|---|---|
| n | % | |||
| 24-28 weeks | ||||
| 1st TP | (1) non PS-UI | 309 | 41.15 | |
| (2) Early PS-UI | 442 | 58.85 | ||
| 36-38 weeks | ||||
| 2nd TP | (1) non PS-UI | 167 | 49.0 | |
| (2) Late PS-UI | 174 | 51.0 | ||
| 1st and 2nd TP | ||||
| (1) non-PS-UI | 376 | 37.9 | ||
| (2) PS-UI | 616 | 62.1 |
| Variable | 1st TP | 2nd TP | ||||||
|---|---|---|---|---|---|---|---|---|
| non PS-UI (n=309) | Early PS-UI (n=442) | p-value | non PS-UI (n=167) | Late PS-UI (n=174) | p-value | |||
| Partnership status | Married | 261 (84.5%) | 367 (83%) | 0.601 | 136 (82.4%) | 148 (85.1%) | 0.511 | |
| Not-married | 48 (15.5%) | 75 (17%) | 29 (17.6%) | 26 (14.9%) | ||||
| Education level | basic level | 22 (7.1%) | 27 (6.1%) | 0.007 | 11 (6.6%) | 15 (8.7%) | 0.210 | |
| high school | 191 (61.8%) | 319 (72.5%) | 93 (55.7%) | 108 (62.4%) | ||||
| college/university | 96 (31.1%) | 94 (21.4%) | 63 (5.2%) | 50 (28.9%) | ||||
| Ethnicity | Caucasian | 253 (82.4%) | 365 (82.6%) | 0.952 | 124 (76.1%) | 130 (75.1%) | 0.843 | |
| Non-caucasian | 54 (17.6%) | 77 (17.4%) | 39 (23.9%) | 43 (24.9%) | ||||
| Pregestational BMI (kg/m2) | 27.04 ± 6.28 | 28.5 ± 7.33 | 0.003 | 27.31 ± 6.42 | 29.47 ± 6.69 | 0.003 | ||
| BMI - 1st TP (kg/m2) | 29.49 ± 6.1 | 30.83 ± 6.87 | 0.005 | 29.58 ± 6.8 | 30.24 ± 6.64 | 0.637 | ||
| BMI - 2nd TP (kg/m2) | 31.23 ± 6.76 | 33.49 ± 6.33 | 0.213 | 31.67 ± 6.2 | 33.92 ± 6.64 | 0.002 | ||
| Gestational weight gain - 1st TP (kg) | 6.31 ± 5.01 | 6.09 ± 6.26 | 0.614 | 6.18 ± 7.73 | 5.85 ± 4.97 | 0.833 | ||
| Gestational weight gain - 2nd TP (kg) | 10.81 ± 5.55 | 10.62 ± 8.76 | 0.863 | 11.6 ± 8.18 | 11.81 ± 6.83 | 0.802 | ||
| Fasting blood glucose (mg/dL) | 79.86 ± 12.4 | 79.42 ± 12.23 | 0.691 | 81.63 ± 13.26 | 82.12 ± 19.37 | 0.826 | ||
| OGTT - fasting (mg/dL) | 74.58 ± 12.83 | 75.77 ± 10.58 | 0.206 | 78.46 ± 11.73 | 77.84 ± 13.2 | 0.755 | ||
| OGTT- 1 h (mg/dL) | 115.65 ± 29.98 | 118.24 ± 32.9 | 0.311 | 126.02 ± 35.13 | 123.81 ± 31.5 | 0.755 | ||
| OGTT - 2 h (mg/dL) | 105.08 ± 26.77 | 106.19 ± 28.86 | 0.615 | 112.05 ± 33.39 | 111.15 ± 28.87 | 0.862 | ||
| Chronic coughing | 0 | 1 (0.3%) | 0.426 | 0 | 8 (6.7%) | 0.012 | ||
| Constipation | 79 (31.6%) | 113 (28.7%) | 0.430 | 27 (27.8%) | 39 (29.5%) | 0.778 | ||
| Fecal incontinence | 1 (0.4%) | 3 (0.8%) | 0.568 | 2 (2.2%) | 3 (2.5%) | 0.879 | ||
| Previous arterial hypertension | 17 (6.8%) | 29 (7.3%) | 0.795 | 12 (12.4%) | 24 (19.4%) | 0.163 | ||
| Alcohol | 1 (0.4%) | 4 (1%) | 0.391 | 0 | 5 (4.2%) | 0.047 | ||
| Smoking | 8 (3.2%) | 19 (4.8%) | 0.328 | 6 (6.6%) | 7 (5.9%) | 0.832 | ||
| Physical activity | 53 (21.4%) | 51 (12.8%) | 0.004 | 22 (22.9%) | 25 (20.7%) | 0.689 | ||
| Gestational diabetes mellitus | 70 (23.0%) | 103 (23.5%) | 0.877 | 116 (70.7%) | 121 (70.3%) | 0.939 | ||
| Pregnancy-induced hypertension | 0 | 3 (4.2%) | 0.185 | 3 (3.8%) | 5 (4.6%) | 0.778 | ||
| Urinary infection | 1 (2.6%) | 7 (9.5%) | 0.184 | 9 (11.3%) | 15 (14.4%) | 0.526 | ||
| Variable | Early PS-UI (n=442) | Late PS-UI (n=442) | PS-UI (1st plus 2nd TP) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR* | 95% CI** | p - value | OR* | 95% CI** | p - value | OR* | 95% CI** | p - value | ||||||
| Education level | basic level | |||||||||||||
| high school | 1.28 | 0.62 ; 2.63 | 0.172 | 0.62 | 0.04 | 9.28 | 0.491 | 1.21 | 0.58 ; 2.51 | 0.304 | ||||
| college/university | 0.89 | 0.40 ; 1;96 | 0.359 | 1.20 | 0.08 ; 19.02 | 0.629 | 0.91 | 0.41 ; 2.04 | 0.493 | |||||
| Ethnicity | Caucasian | 1.22 | 0.76 ; 1.96 | 0.416 | 2.65 | 0.46 ; 15.15 | 0.274 | 1.28 | 0.88 ; 0.78 | 0.519 | ||||
| Non-caucasian | ||||||||||||||
| Age (years) | 0.99 | 0.96 ; 1.02 | 0.375 | 1.01 | 0.92 ; 1.12 | 0.805 | 0.99 | 0.96 ; 1.03 | 0.706 | |||||
| Pregestational BMI | 1.03 | 1.01 ; 1.06 | 0.014 | 1.02 | 0.93 ; 1.11 | 0.716 | 1.04 | 1.01 ; 1.07 | 0.006 | |||||
| Constipation | 1.21 | 0.84 ; 0.83 | 0.312 | 1.02 | 0.26 ; 4.03 | 0.974 | 0.78 | 0.54 ; 1.13 | 0.193 | |||||
| Fecal incontinence | 3.02 | 0.29 ; 31.82 | 0.358 | 2.81 | 0.26 ; 29.92 | 0.392 | ||||||||
| Previous arterial hypertension | 0.83 | 0.41 ; 1.70 | 0.616 | 1.4 | 0.16 ; 12.32 | 0.761 | 0.84 | 0.41 ; 1.76 | 0.652 | |||||
| Smoking | 2.08 | 0.78 ; 5.53 | 0.141 | 1.85 | 0.69 ; 4.91 | 0.220 | ||||||||
| Physical activity | 0.51 | 0.32 ; 0.80 | 0.003 | 0.72 | 0.13 ; 3.88 | 0.700 | 0.5 | 0.32 ; 0.79 | 0.003 | |||||
| Gestational diabetes mellitus | 1.10 | 1.01 ; 1.06 | 0.649 | 0.94 | 0.25 ; 3.58 | 0.928 | 1.16 | 0.75 ; 1.81 | 0.500 | |||||
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