Version 1
: Received: 31 October 2023 / Approved: 1 November 2023 / Online: 1 November 2023 (04:06:48 CET)
How to cite:
Onal, P.; Bozaykut, A. Analysis of Hemogram and C-reactive protein in Viral Gastroenteritis: Insights into Inflammatory Response. Preprints2023, 2023110012. https://doi.org/10.20944/preprints202311.0012.v1
Onal, P.; Bozaykut, A. Analysis of Hemogram and C-reactive protein in Viral Gastroenteritis: Insights into Inflammatory Response. Preprints 2023, 2023110012. https://doi.org/10.20944/preprints202311.0012.v1
Onal, P.; Bozaykut, A. Analysis of Hemogram and C-reactive protein in Viral Gastroenteritis: Insights into Inflammatory Response. Preprints2023, 2023110012. https://doi.org/10.20944/preprints202311.0012.v1
APA Style
Onal, P., & Bozaykut, A. (2023). Analysis of Hemogram and C-reactive protein in Viral Gastroenteritis: Insights into Inflammatory Response. Preprints. https://doi.org/10.20944/preprints202311.0012.v1
Chicago/Turabian Style
Onal, P. and Abdulkadir Bozaykut. 2023 "Analysis of Hemogram and C-reactive protein in Viral Gastroenteritis: Insights into Inflammatory Response" Preprints. https://doi.org/10.20944/preprints202311.0012.v1
Abstract
Background: Acute viral gastroenteritis remains a leading cause of health care cost globally, prompting the need for basic diagnostic strategies. Objectives: This study aims to assess the impact of viral gastroenteritis on hemogram and C-reactive protein. Methods: By conducting a retrospective study, three groups of children diagnosed with gastroenteritis (rotavirus positive, adenovirus positive and rota/adenovirus negative group) were compared in terms of hemogram parameters and C- reactive protein. Results: Among 756 children with gastroenteritis, 7.9% of patients were rotavirus positive and 6.5% of them were adenovirus positive. Our findings disclosed a statistically significant association between low lymphocyte (2.2 ± 1.45) and MPV value (7.38 ± 0.4 fL) with rotavirus gastroenteritis. Also, the analysis revealed a high neutrophil/lymphocyte ratio (2.8± 2.1) in rotavirus group. However, our study did not reveal any prominent laboratory marker that serves as a distinctive feature of adenovirus unlike rotavirus. Conclusions: In conclusion our research highlights the potential of decreased mean platelet volume and lymphopenia as diagnostic markers for rotavirus gastroenteritis.
Keywords
rotavirus; adenovirus; children; gastroenteritis ; mean platelet volume; neutrophil/lymphocyte value
Subject
Medicine and Pharmacology, Pediatrics, Perinatology and Child Health
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
