PreprintReviewVersion 1Preserved in Portico This version is not peer-reviewed
Comparative Analysis of Cardiac Resynchronisation Therapy Upgrades in Patients with Icd And Pacemakers with Chronic Right Ventricle Pacing-Induced Cardiomyopathy
Version 1
: Received: 6 June 2023 / Approved: 7 June 2023 / Online: 7 June 2023 (02:32:17 CEST)
How to cite:
Farhangee, A.; Davies, M.; Mindrila, I.; Meyrick, R.; Gaughan, K.; Morgan, D.; Sieniewicz, B. Comparative Analysis of Cardiac Resynchronisation Therapy Upgrades in Patients with Icd And Pacemakers with Chronic Right Ventricle Pacing-Induced Cardiomyopathy. Preprints2023, 2023060470. https://doi.org/10.20944/preprints202306.0470.v1
Farhangee, A.; Davies, M.; Mindrila, I.; Meyrick, R.; Gaughan, K.; Morgan, D.; Sieniewicz, B. Comparative Analysis of Cardiac Resynchronisation Therapy Upgrades in Patients with Icd And Pacemakers with Chronic Right Ventricle Pacing-Induced Cardiomyopathy. Preprints 2023, 2023060470. https://doi.org/10.20944/preprints202306.0470.v1
Farhangee, A.; Davies, M.; Mindrila, I.; Meyrick, R.; Gaughan, K.; Morgan, D.; Sieniewicz, B. Comparative Analysis of Cardiac Resynchronisation Therapy Upgrades in Patients with Icd And Pacemakers with Chronic Right Ventricle Pacing-Induced Cardiomyopathy. Preprints2023, 2023060470. https://doi.org/10.20944/preprints202306.0470.v1
APA Style
Farhangee, A., Davies, M., Mindrila, I., Meyrick, R., Gaughan, K., Morgan, D., & Sieniewicz, B. (2023). Comparative Analysis of Cardiac Resynchronisation Therapy Upgrades in Patients with Icd And Pacemakers with Chronic Right Ventricle Pacing-Induced Cardiomyopathy. Preprints. https://doi.org/10.20944/preprints202306.0470.v1
Chicago/Turabian Style
Farhangee, A., David Morgan and Ben Sieniewicz. 2023 "Comparative Analysis of Cardiac Resynchronisation Therapy Upgrades in Patients with Icd And Pacemakers with Chronic Right Ventricle Pacing-Induced Cardiomyopathy" Preprints. https://doi.org/10.20944/preprints202306.0470.v1
Abstract
Background: This is a comparative analysis of upgrade to cardiac resynchronisation therapy (CRT) of an existing pacemaker implanted for bradyarrhythmia or an implantable cardioverter defibrillator (ICD). International guidelines recommend an upgrade to CRT for both groups based on the same criteria; this may lead to a hypothesis of whether we are under-treating a population that would otherwise benefit more from a CRT than the other. Methods: So far, this is the largest multicentre retrospective study that includes in total, 151 (93 upgrades to CRT-P and 58 upgrades to CRT-D) participants who had an upgrade to a CRT device between January 2010 and January 2020. Clinical and echocardiographic parameters were analysed both, before and after an upgrade to CRT. Results: EF was greater in patients with PPM, both before and after upgrade. Moreover, the post upgrade increase in EF was significantly greater in patients with PPM. Patients with ICD have, on average, an NYHA class ranking greater than PPM patients, both before and after upgrade. Conclusions: These data show that the PPM group patients have a greater response to upgrade to CRT compared to those from the ICD group. It also demonstrates that patients with non-ischaemic cardiomyopathy are better responders compared to those with ischaemic aetiology.
Public Health and Healthcare, Health Policy and Services
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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