Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Controls of Central and Peripheral Blood Pressure and Hemorrhagic/Hypovolemic Shock

Version 1 : Received: 29 November 2022 / Approved: 2 December 2022 / Online: 2 December 2022 (02:00:06 CET)

A peer-reviewed article of this Preprint also exists.

Ranjan, A.K.; Gulati, A. Controls of Central and Peripheral Blood Pressure and Hemorrhagic/Hypovolemic Shock. J. Clin. Med. 2023, 12, 1108. Ranjan, A.K.; Gulati, A. Controls of Central and Peripheral Blood Pressure and Hemorrhagic/Hypovolemic Shock. J. Clin. Med. 2023, 12, 1108.

Abstract

The pressure exerted on the heart and blood vessels because of blood flow is considered as an important parameter for the cardiovascular function. It determines sufficient blood perfusion as well as transportation of nutrition, oxygen and other essential factors to every organ. Pressure in the primary arteries located near the heart and the brain, known as central blood pressure (CBP), while in peripheral arteries, known as peripheral blood pressure (PBP). Normally, CBP and PBP are correlated; however, cardiovascular disorders interfere their regulation and affect the blood flow in vital organs and accessory organs, differently. Therefore, understanding each of them in normal and disease conditions is essential for managing various cardiovascular disorders and increasing their treatment outcomes. In this review, we have described the control systems (neural, hormonal, osmotic and cellular) of the blood pressure and its regulation in hypovolemic shock using centhaquine (Lyfaquin®) as a resuscitative agent.

Keywords

Blood Pressure; Cardiovascular Disorder; Hypertension; Hypotension; Hypoxia; Baroreflex; Hemorrhagic Shock; Hypovolemic Shock; Vasopressure; Resuscitation; Centhaquine (Lyfaquin); Sympathetic System; Parasympathetic System; Adrenoreceptors

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

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