Version 1
: Received: 1 November 2022 / Approved: 3 November 2022 / Online: 3 November 2022 (12:08:08 CET)
How to cite:
Abujabal, M.; Shalaby, M.A.; Abdullah, L.; Albanna, A.S.; Elzoghby, M.; Sethi, S.K.; Temsah, M.; Aljamaan, F.; Alhasan, K.; Kari, J.A. Common Prognostic Biomarkers and Outcomes in Patients with COVID-19 Infection. Preprints2022, 2022110079. https://doi.org/10.20944/preprints202211.0079.v1
Abujabal, M.; Shalaby, M.A.; Abdullah, L.; Albanna, A.S.; Elzoghby, M.; Sethi, S.K.; Temsah, M.; Aljamaan, F.; Alhasan, K.; Kari, J.A. Common Prognostic Biomarkers and Outcomes in Patients with COVID-19 Infection. Preprints 2022, 2022110079. https://doi.org/10.20944/preprints202211.0079.v1
Abujabal, M.; Shalaby, M.A.; Abdullah, L.; Albanna, A.S.; Elzoghby, M.; Sethi, S.K.; Temsah, M.; Aljamaan, F.; Alhasan, K.; Kari, J.A. Common Prognostic Biomarkers and Outcomes in Patients with COVID-19 Infection. Preprints2022, 2022110079. https://doi.org/10.20944/preprints202211.0079.v1
APA Style
Abujabal, M., Shalaby, M.A., Abdullah, L., Albanna, A.S., Elzoghby, M., Sethi, S.K., Temsah, M., Aljamaan, F., Alhasan, K., & Kari, J.A. (2022). Common Prognostic Biomarkers and Outcomes in Patients with COVID-19 Infection. Preprints. https://doi.org/10.20944/preprints202211.0079.v1
Chicago/Turabian Style
Abujabal, M., Khalid Alhasan and Jameela A. Kari. 2022 "Common Prognostic Biomarkers and Outcomes in Patients with COVID-19 Infection" Preprints. https://doi.org/10.20944/preprints202211.0079.v1
Abstract
Abstract: Background: COVID-19 is a respiratory disease that eventually became pandemic with 300 million people infected around the world. Alongside the improvement in COVID-19 management and vaccine development, identifying biomarkers for COVID-19 has recently reported to help in early prediction and managing severe cases which might improve outcome. The Aim of our study was to find out if there is any correlation between clinical severity and elevated hematological and biochemical markers in Covid-19 patients and its effect on the outcome Methods: We have collected data retrospectively of socio-demographic, medical history, biomarkers, and diseases outcome from five hospitals and health institutions in the Kingdom of Saudi Arabia. Results: Pneumonia was the most common presentation of COVID 19 in our cohort. All biomarkers (D-Dimer, CRP, troponin, LDH and ferritin) except for the mean lowest white blood cells were found to have significant correlation (p<0.05) with worse COVID-19 disease outcomes. There was a sig-nificant association between the inflammatory biomarkers and the disease severity of COVID 19 patients (p<0.001). Patients with evidence of severe respiratory disease particularly who required mechanical ventilation (MV) had higher biomarkers, when compared to those with stable respiratory condition (p<0.001). Conclusion: Identifying biomarkers predicts outcome for COVID-19 patients and may significantly help in the management.
Keywords
Biomarkers; COVID-19; Common Prognostic Biomarkers
Subject
Medicine and Pharmacology, Clinical Medicine
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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