Working Paper Review Version 2 This version is not peer-reviewed

A Literature Review of 2019 Novel Coronavirus During the Early Outbreak Period: Epidemiology, Causes, Clinical Manifestation and Diagnosis, Prevention and Control

Version 1 : Received: 4 February 2020 / Approved: 5 February 2020 / Online: 5 February 2020 (10:54:11 CET)
Version 2 : Received: 5 February 2020 / Approved: 6 February 2020 / Online: 6 February 2020 (08:54:11 CET)

A peer-reviewed article of this Preprint also exists.

Adhikari, S., Meng, S., Wu, Y. et al. Epidemiology, causes, clinical manifestation and diagnosis, prevention and control of coronavirus disease (COVID-19) during the early outbreak period: a scoping review. Infect Dis Poverty 9, 29 (2020). https://doi.org/10.1186/s40249-020-00646-x Adhikari, S., Meng, S., Wu, Y. et al. Epidemiology, causes, clinical manifestation and diagnosis, prevention and control of coronavirus disease (COVID-19) during the early outbreak period: a scoping review. Infect Dis Poverty 9, 29 (2020). https://doi.org/10.1186/s40249-020-00646-x

Journal reference: Infectious Diseases of Poverty 2020, 9
DOI: 10.1186/s40249-020-00646-x

Abstract

The 2019-nCoV has been identified as the cause of an outbreak of respiratory illness in Wuhan, Hubei Province, China beginning in December 2019. This epidemic had spread to 19 countries with 11,791 confirmed cases, including 213 deaths, as of January 31, 2020. The World Health Organization declared it as a Public Health Emergency of International Concern. This study analyzed and discussed 70 research articles published until January 31, 2020 for a better understanding of the epidemiology, causes, clinical diagnosis, prevention and control of this virus. Studies thus far have shown origination in connection to a seafood market in Wuhan, but specific animal association has not been confirmed. The reported symptoms include fever, cough, fatigue, pneumonia, headache, diarrhea, hemoptysis, and dyspnea. Preventive measures such as masks, hand hygiene practices, avoidance of public contact, case detection, contact tracing, and quarantines are effective for reducing the transmission. To date, no specific antiviral treatment is proven effective, hence, infected people primarily rely on symptomatic treatment and supportive care. Although these studies had relevance to control a public emergency, more research need to be conducted to provide valid and reliable ways to manage this kind of public health emergency in both short- and long- term.

Subject Areas

2019-nCoV; epidemiology; causes; prevention and control; review

Comments (1)

Comment 1
Received: 6 February 2020
Commenter: Sasmita Poudel Adhikari
Commenter's Conflict of Interests: Author
Comment: We have incorporated minor revision in the methodology section.
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