Galectin-13 and Laeverin Levels Interfere with the Fetoplacental Growth

Márió Vincze; János Sikovanyecz Jr.; Imre Földesi; Andrea Surányi; Szabolcs Várbíró; Gábor Németh; János Sikovanyecz; Zoltán Kozinszky

doi:10.20944/preprints202404.1482.v1

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preprints.org > medicine and pharmacology > obstetrics and gynaecology > doi: 10.20944/preprints202404.1482.v1

Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Galectin-13 and Laeverin Levels Interfere with the Fetoplacental Growth

Márió Vincze

János Sikovanyecz Jr.

Version 1 : Received: 22 April 2024 / Approved: 22 April 2024 / Online: 23 April 2024 (13:18:16 CEST)

How to cite: Vincze, M.; Sikovanyecz Jr., J.; Földesi, I.; Surányi, A.; Várbíró, S.; Németh, G.; Sikovanyecz, J.; Kozinszky, Z. Galectin-13 and Laeverin Levels Interfere with the Fetoplacental Growth. Preprints 2024, 2024041482. https://doi.org/10.20944/preprints202404.1482.v1 Vincze, M.; Sikovanyecz Jr., J.; Földesi, I.; Surányi, A.; Várbíró, S.; Németh, G.; Sikovanyecz, J.; Kozinszky, Z. Galectin-13 and Laeverin Levels Interfere with the Fetoplacental Growth. Preprints 2024, 2024041482. https://doi.org/10.20944/preprints202404.1482.v1

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MDPI and ACS Style

Vincze, M.; Sikovanyecz Jr., J.; Földesi, I.; Surányi, A.; Várbíró, S.; Németh, G.; Sikovanyecz, J.; Kozinszky, Z. Galectin-13 and Laeverin Levels Interfere with the Fetoplacental Growth. Preprints 2024, 2024041482. https://doi.org/10.20944/preprints202404.1482.v1

APA Style

Vincze, M., Sikovanyecz Jr., J., Földesi, I., Surányi, A., Várbíró, S., Németh, G., Sikovanyecz, J., & Kozinszky, Z. (2024). Galectin-13 and Laeverin Levels Interfere with the Fetoplacental Growth. Preprints. https://doi.org/10.20944/preprints202404.1482.v1

Chicago/Turabian Style

Vincze, M., János Sikovanyecz and Zoltán Kozinszky. 2024 "Galectin-13 and Laeverin Levels Interfere with the Fetoplacental Growth" Preprints. https://doi.org/10.20944/preprints202404.1482.v1

Abstract

Introduction: Galectin-13 (Gal-13) is predominantly produced by the syncytiotrophoblast, while laeverin is expressed on the outgrowing extravillous trophoblast, and both are thought to be biomarkers of preeclampsia. The aim of this study was to assess the correlation between concentrations of Gal-13 and laeverin measured in maternal serum and amniotic fluid at 16-22 weeks of gestation and the sonographic assessment of the fetoplacental measurements. Materials and methods: Fetal biometric data, and placental volume and perfusion indices were measured in 62 singleton pregnancies. Serum and amniotic levels of Gal-13 and laeverin levels were measured using a sandwich ELISA. Results: Both amniotic fluid and serum Gal-13 levels expressed a negative correlation to the plasma laeverin level in mid-pregnancy. Serum laeverin level correlated positively with the gestational length at delivery (β=0.39, p

Keywords

Gal-13; laeverin; serum; amniotic fluid; fetus; placenta; sonography

Subject

Medicine and Pharmacology, Obstetrics and Gynaecology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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